Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Constipation Age: Adult |
Dose: Oral – 5-10 mg Frequency: once daily Note: as a single dose, usually at bedtime |
|
Indication: Bowel evacuation before investigational procedures Age: Adult |
Dose: Oral – 10 mg Frequency: given in the morning and again in the afternoon of the day before examination Note: with Magnesium citrate |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Constipation Age: 1 month to less than 4 years |
Dose: Oral – 0.25 mg/kg Note: Maximum: 5 mg; Doses are usually given at night. |
|
Indication: Constipation Age: 4-10 years |
Dose: Oral – 2.5-5 mg Note: Doses are usually given at night. |
Administration
- May take with or without food
- Take with plenty of water
Side Effect
- Abdominal discomfort (eg abdominal pain and cramps)
- diarrhoea
- Rarely
- allergic reactions (eg skin reactions, angioedema)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Diuretics (Chlorothiazide, Chlorthalidone, Hydrochlorothiazide, Indapamide, Metolazone, Bumetanide, Ethacrynic acid, Furosemide, Torsemide, Amiloride, Eplerenone, Spironolactone, Triamterene), adreno-Corticosteroids (Prednisone, Prednisolone, Methylprednisolone, Dexamethasone, Hydrocortisone)
|
Increased risk of electrolyte imbalance
|
|
Cardiac glycosides
|
Increased sensitivity resulting from electrolyte imbalance
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Acute inflammatory bowel disease
|
Can worsen inflammation
|
|
Severe dehydration
|
Risk of electrolyte imbalance
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.