Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Acute bronchospasm Age: Adult |
Dose: Oral – 2-4 mg Frequency: 3 or 4 times daily Note: Up to 8 mg 3 or 4 times daily. |
|
Indication: Acute bronchospasm Age: Adult |
Dose: Oral modified-release tablet – 8 mg Frequency: twice daily Note: Not to exceed 32 mg/day. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Acute bronchospasm Age: 2-6 years |
Dose: Tablet – 1-2 mg Frequency: 3 or 4 times daily Note: maximum 8 mg 3 or 4 times daily |
|
Indication: Acute bronchospasm Age: greater than 6-12 years |
Dose: Tablet – 2 mg Frequency: 3 or 4 times daily Note: maximum 8 mg 3 or 4 times daily |
Administration
- Inhaler: Shake well before use
- Breathe out fully before inhaling
Side Effect
- Tremor (20%)
- Nervousness in children aged 2-6 years (20%)
- Insomnia in children aged 6-12 years receiving 4-12 mg q12hour(11%)
- Nausea (10%)
- Fever (1.6-9%)
- Bronchospasm (8%)
- Vomiting (7%)
- Headache (4-7%)
- Dizziness (1-7%)
- Cough (5%)
- Allergic reactions (4%)
- Otitis media (3.3%)
- Epistaxis in children (3%)
- Increased appetite (3%)
- Urinary Tract Infection (UTI) (3%)
- Dry mouth (Less than 3%)
- Eructation or flatulence (Less than 3%)
- Increased sweating (Less than 3%)
- Pain (2.7%)
- Dyspepsia (1-2%)
- Hyperactivity (1-2%)
- Chills (Less than 2%)
- Lymphadenopathy (Less than 2%)
- Ocular pruritus (Less than 2%)
- Sweating (Less than 2%)
- Conjunctivitis in children aged 2-6 years (1%)
- Dysphonia (More than 1%)
- Flu syndrome
- Nervousness
- Epigastric pain
- Epistaxis in adults
- Hyperactivity in children
- Adverse reactions such as hypertension
- angina
- vertigo
- central nervous system stimulation
- insomnia
- headache
- metabolic acidosis
- and drying or irritation of oropharynx
- Hypersensitivity
- Hypokalemia
- Increased blood glucose levels
- Prolonged QT interval and ST-segment depression
- Sleeplessness
- Tachycardia (incidence varies with formulation)
- Urticaria
- angioedema
- rash
- bronchospasm
- and oropharyngeal edema (rare)
- Potentially serious hypokalaemia after large doses
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Diuretics (Chlorothiazide, Chlorthalidone, Hydrochlorothiazide, Indapamide, Metolazone, Bumetanide, Ethacrynic acid, Furosemide, Torsemide, Amiloride, Eplerenone, Spironolactone, Triamterene), Corticosteroids (Prednisone, Prednisolone, Methylprednisolone, Dexamethasone, Hydrocortisone), Xanthines
|
May augment hypokalemia
|
|
MAOIs (Phenelzine, Tranylcypromine, Selegiline, Moclobemide), TCAs, Sympathomimetics (Ephedrine, Pseudoephedrine, Phenylephrine)
|
Potentiated CV effects
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Hypersensitivity
|
Risk of severe allergic reactions
|
|
Placenta Praevia
|
Can worsen pregnancy complications
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.