Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Type 2 diabetes mellitus
Age: Adult
Dose: Immediate-release tablet – 1 tablet
Frequency: twice daily
Note: Take with meals, with gradual dose escalation to reduce the gastrointestinal adverse effects due to metformin. Maximum: Empagliflozin 25 mg and metformin 2,000 mg daily.
Indication: Type 2 diabetes mellitus
Age: Adult
Dose: Extended-release tablet – 1 tablet
Frequency: once daily
Note: Take with a meal in the morning, with gradual dose escalation to reduce the gastrointestinal adverse effects due to metformin. Maximum: Empagliflozin 25 mg and metformin 2,000 mg daily.

Child Dose

Clinical InformationAdministration Information
Indication: Type 2 diabetes mellitus
Age: 10 years and older
Condition: New to both components
Dose: Oral – 5 mg empagliflozin/500 mg metformin
Frequency: Twice daily
Note: Dose individualized based on current regimen; Route: Oral; Maximum Dose: Empagliflozin 25 mg and metformin 2,000 mg per day

Renal Dose

Clinical InformationAdministration Information
Condition: Renal impairment
Dose: Dose:
Note: Contraindicated
Administration
  • Take with meals
  • Take at regular intervals
Side Effect

Drug Interaction

Drug NameRisk Factors
Thiazides and loop diuretics (Furosemide, Bumetanide, Ethacrynic acid, Torsemide)
May potentiate diuretic effect and increased risk of hypotension
UGT enzyme inhibitor (e.g. probenecid)
Increased plasma concentration of empagliflozin

Disease Interaction

Disease NameRisk Factors
Diabetic Pre-Coma
Risk of metabolic crisis
Acute Metabolic Acidosis
Risk of life-threatening acidosis

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature, protected from light & moisture. Keep out of the reach of children.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.