Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Acute psychosis, Acute episodes Age: Adult |
Dose: Oral – 400—800 mg daily Frequency: in two divided doses Note: Adjust according to response; maximum 1.2g daily. |
|
Indication: Mixed positive and negative symptoms Age: Adult |
Dose: Oral Note: adjust dose to control positive symptoms. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Under 18 years |
Dose: Tablet – Not recommended Note: Under 18 years, not recommended. |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal Impairment Creatinine Clearance 10-30 mL/min |
Dose: Dosage – One-third of the usual dose Note: For use in patients with stable renal function |
|
Condition: Renal Impairment Creatinine Clearance 31-60 mL/min |
Dose: Dosage – Half the usual dose Note: For use in patients with stable renal function |
Administration
- Take regularly at prescribed times
- Follow doctor's instructions for with/without food
Side Effect
- tremor
- rigidity
- hypokinesia
- hypersalivation
- akathisia
- dyskinesia
- Common Insomnia
- anxiety
- agitation
- orgasmic dysfunction
- Common Constipation
- nausea
- vomiting
- dry mouth
- Common Amisulpride causes an increase in plasma prolactin levels which is reversible after drug discontinuation
- This may result in galactorrhoea
- amenorrhoea
- gynaecomastia
- breast pain
- and erectile dysfunction
- Uncommon Hyperglycaemia
- Common Hypotension
- Uncommon Bradycardia
- Common Weight gain
- Uncommon Elevations of hepatic enzymes, mainly transaminases
- Uncommon Allergic reaction
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Other Antipsychotics (Haloperidol, Risperidone, Quetiapine, Olanzapine, Clozapine, Aripiprazole), drugs that prolong QT interval, levodopa, CNS depressants, alcohol, Antihypertensive (Captopril, Enalapril, Lisinopril, Ramipril, Benazepril, Fosinopril, Quinapril, Perindopril, Losartan, Valsartan, Candesartan, Irbesartan, Telmisartan, Olmesartan, Propranolol, Metoprolol, Atenolol, Carvedilol, Bisoprolol, Nadolol, Amlodipine, Diltiazem, Verapamil, Nifedipine, Nicardipine, Hydrochlorothiazide, Chlorthalidone, Indapamide, Furosemide, Bumetanide, Torsemide, Spironolactone, Amiloride, Triamterene, Prazosin, Doxazosin, Terazosin, Clonidine, Methyldopa, Hydralazine, Minoxidil)
|
Interactions mentioned but specific effects not detailed
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Prolactin-Dependent Tumors
|
Risk of tumor growth
|
|
Pheochromocytoma
|
Risk of hypertensive crisis
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.