Question 1

What is this medicine for, and how does it work?

Accepted Answer

This is a retinoid. It regulates skin cell growth. It is used to treat severe acne and other skin conditions.

Question 2

When and how should this medicine be taken?

Accepted Answer

• Take with food • Take twice daily • Complete prescribed course

Question 3

When should this medicine not be used?

Accepted Answer

• Do not use during pregnancy • Do not use if you have severe liver disease • Do not use if you have severe hyperlipidemia • Do not use with vitamin A supplements

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• SEVERE BIRTH DEFECT RISK - Absolutely contraindicated in pregnancy • Must use two effective forms of contraception • Monthly pregnancy tests required • Regular blood tests to monitor liver function • Watch for signs of depression and suicidal thoughts • Can cause severe dry skin and sensitivity to sun • Monthly doctor visits required • Avoid blood donation during treatment and for 1 month after • Report mood changes, severe headaches, or vision changes immediately

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• Not safe during pregnancy; • May cause severe birth defects; • Avoid use and use contraception

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• SEVERE BIRTH DEFECT RISK - Absolutely contraindicated in pregnancy • Must use two effective forms of contraception • Monthly pregnancy tests required • Regular blood tests to monitor liver function • Watch for signs of depression and suicidal thoughts • Can cause severe dry skin and sensitivity to sun • Monthly doctor visits required • Avoid blood donation during treatment and for 1 month after • Report mood changes, severe headaches, or vision changes immediately

Question 7

What should be done if a dose is missed?

Accepted Answer

• If you miss a dose, take it as soon as you remember. • However, if it's almost time for your next dose, skip the missed dose. • Never take two doses together. • If taken with meals: Take the dose with your next meal. • For thrice-daily dosing: If more than 2 hours until your next dose, take the missed dose. • Take your next dose at the regular time. • If you're unsure, contact your doctor or pharmacist.

Question 8

What should be done in case of an overdose?

Accepted Answer

• Overdose symptoms: Hypervitaminosis A. • Treatment: Discontinue drug, symptomatic care.

Question 9

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: Dry lips, dry skin/nose, eye irritation, joint pain, skin fragility, increased sun sensitivity• What to do:- Use moisturizers regularly- Avoid sun exposure- Regular blood tests- No alcohol consumption- Report severe mood changes; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 10

What is Akno 10mg used for?

Accepted Answer

Akno 10mg (Isotretinoin) is a pharmaceutical medicine manufactured by Drug International Ltd. in Bangladesh. It is primarily prescribed for Acne, Acne Vulgaris, Inflammatory Acne, Non-Inflammatory Acne.

Question 11

What is the active generic component of Akno?

Accepted Answer

The active ingredient in Akno is Isotretinoin, belonging to the Oral Retinoids For Acne drug class.

Question 12

What is the retail price of Akno 10mg in Bangladesh?

Accepted Answer

The official retail price of Akno 10mg (Capsule) is ৳40.00 in Bangladesh (prices may vary slightly by pack size and authorized pharmacy).

Question 13

What is the recommended dosage for Akno?

Accepted Answer

Standard adult dosage: Oral – 0.5-1 mg/kg/day (divided twice daily). Pediatric dosage: PO – Safety and efficacy not established. Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 14

Is Akno safe during pregnancy and breastfeeding?

Accepted Answer

Akno is classified under Pregnancy Category "X (Capsules: Not Assigned)". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 15

What are the common side effects of Akno?

Accepted Answer

**More than 10%**; Cheilitis (90%);Xerosis;Xerostomia;Dry nose;Epistaxis;Pruritus;Conjunctivitis (including blepharoconjunctivitis) (40%);Irritation (40%);Increased erythrocyte sedimentation rates (40%);Thinning of hair

Clinical Information	Administration Information
Indication: Severe, Recalcitrant Nodular Acne, Severe nodular acne unresponsive to conventional therapy, including systemic antibiotics Age: Adult	Dose: Oral – 0.5-1 mg/kg/day Frequency: divided twice daily Duration: 15-20 weeks Note: Hepatic impairment: Contraindicated.
Indication: Severe nodular acne with scarring or primarily manifested on the trunk Age: Adult Condition: very severe	Dose: Oral – up to 2 mg/kg/day Note: As tolerated. Hepatic impairment: Contraindicated.

Clinical Information	Administration Information
Indication: Severe, Recalcitrant Nodular Acne Age: less than 12 years	Dose: PO – Safety and efficacy not established Note: Severe nodular acne unresponsive to conventional therapy, including systemic antibiotics
Indication: Severe, Recalcitrant Nodular Acne Age: greater than 12 years	Dose: PO – 0.5-1 mg/kg/day Frequency: twice daily Duration: 15-20 weeks Note: Severe nodular acne unresponsive to conventional therapy, including systemic antibiotics

Drug Name	Risk Factors
Vitamin A or its derivatives	Additive toxicity
Microdosed progesterone	Decreased efficacy (use 2 forms of contraception)

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Renal Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources