Question 1

What is this medicine for, and how does it work?

Accepted Answer

This is an anti-cancer medication. It's used to treat a specific type of lung cancer. It works by blocking an enzyme that helps cancer cells grow.

Question 2

When and how should this medicine be taken?

Accepted Answer

• Take with or without food • Take at same time each day • Swallow tablet whole • Take with water

Question 3

When should this medicine not be used?

Accepted Answer

• Lung problems • Vision problems • High blood pressure • Pregnancy

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• Can cause serious lung problems, report any breathing difficulties immediately • May cause vision problems, report any vision changes to your doctor • Can cause high blood pressure, monitor blood pressure regularly • May harm unborn babies, use effective contraception

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• Can cause fetal harm • Verify pregnancy status before treatment • Use effective non-hormonal contraception during and after treatment

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• Can cause serious lung problems, report any breathing difficulties immediately • May cause vision problems, report any vision changes to your doctor • Can cause high blood pressure, monitor blood pressure regularly • May harm unborn babies, use effective contraception

Question 7

Is this medicine suitable for children and elderly?

Accepted Answer

• Safety unknown in children • No overall differences in safety for elderly

Question 8

What should be done if a dose is missed?

Accepted Answer

• If you miss a dose, take it as soon as you remember. • However, if it's almost time for your next dose, skip the missed dose. • Never take two doses together. • For once-daily dosing: If you remember on the same day, take the dose. • For twice-daily dosing: If more than 6 hours until your next dose, take the missed dose. • Take your next dose at the regular time. • If you're unsure, contact your doctor or pharmacist.

Question 9

What should be done in case of an overdose?

Accepted Answer

• Symptoms: Hypertension, bradycardia, pulmonary toxicity. • Treatment: BP monitoring, monitor pulmonary function.

Question 10

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: Elevated enzymes, high blood sugar, nausea, fatigue, breathing problems • What to do: Regular blood tests; Monitor blood sugar; Report breathing issues; Follow-up regularly; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 11

What is ALK 90 used for?

Accepted Answer

ALK 90 (Brigatinib) is a pharmaceutical medicine manufactured by Jenphar Bangladesh Ltd. in Bangladesh. It is primarily prescribed for Non-Small Cell Lung Cancer (NSCLC).

Question 12

What is the active generic component of ALK?

Accepted Answer

The active ingredient in ALK is Brigatinib.

Question 13

What is the retail price of ALK 90 in Bangladesh?

Accepted Answer

The official retail price of ALK 90 (Tablet) is ৳1034.00 in Bangladesh (prices may vary slightly by pack size and authorized pharmacy).

Question 14

What is the recommended dosage for ALK?

Accepted Answer

Standard adult dosage: Oral – 90 mg (once daily). Pediatric dosage: Tablet – No approved pediatric dosage available. Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 15

Is ALK safe during pregnancy and breastfeeding?

Accepted Answer

ALK is classified under Pregnancy Category "Not Assigned". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 16

What are the common side effects of ALK?

Accepted Answer

**More than 10%**; Increased AST (38%);Hyperglycemia (38%);Increased ALT (34%);Nausea (33%);Fatigue (29%);Headache (28%);Increased CPK (27%);Increased amylase (27%);Dyspnea (27%);Vomiting (24%);Anemia (23%);Decreased app

Clinical Information	Administration Information
Indication: Anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer Age: Adult	Dose: Oral – 90 mg Frequency: once daily Duration: first 7 days Note: As detected by an FDA-approved test.
Indication: Anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer Age: Adult	Dose: Oral – 180 mg Frequency: once daily Note: Increase to this dose after the first 7 days. Continue until disease progression or unacceptable toxicity. As detected by an FDA-approved test.

Clinical Information	Administration Information
Condition: Renal impairment Mild or moderate (Creatinine Clearance 30-89 mL/min)	Dose: Tablet – Dosage not specified Note: No dose adjustment required
Condition: Renal impairment Severe (Creatinine Clearance 15-29 mL/min)	Dose: Tablet – Reduce brigatinib dose by approximately 50% (example: from 180 mg to 90 mg, or from 90 mg to 60 mg) Note: Dosage reduction required for severe renal impairment

Drug Name	Risk Factors
Boceprevir, cobicistat, indinavir, lopinavir, nelfinavir, ritonavir, saquinavir, clarithromycin, itraconazole, ketoconazole, posaconazole, voriconazole, grapefruit juice	Increased plasma concentration and adverse reactions
Rifampin, carbamazepine, phenytoin, St. John's Wort	Decreased plasma concentration and efficacy

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

Is this medicine suitable for children and elderly?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Renal Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources