Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Pharyngitis or Tonsillitis Age: Adults |
Dose: 250 mg Frequency: twice daily Duration: 5-10 days |
|
Indication: Acute bacterial maxillary sinusitis Age: Adults |
Dose: 250 mg Frequency: twice daily Duration: 10 days |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Pharyngitis or Tonsillitis Age: Adolescents (13 years and older) |
Dose: Tablet – 250 mg Frequency: twice daily Duration: 5-10 days |
|
Indication: Acute bacterial maxillary sinusitis Age: Adolescents (13 years and older) |
Dose: Tablet – 250 mg Frequency: twice daily Duration: 10 days |
Administration
- Take with food
- Take at regular intervals
Side Effect
- Diarrhea (4-11%
- depends on duration)
- Decreased hemoglobin or hematocrit (10%)
- Eosinophilia (7%)
- Nausea or vomiting (3-7%)
- Vaginitis (Less than 5%)
- Transient rise in hepatic transaminases (2-4%)
- Diaper rash (3%)
- Increase in alkaline phosphatase (2%)
- Thrombophlebitis (2%)
- Increase in lactate dehydrogenase (1%)
- Anemia
- Cholestasis
- Colitis
- Dyspnea
- Epidermal necrolysis
- Increase in blood urea nitrogen (BUN) and creatinine
- Jaundice
- Nephritis
- Prolonged prothrombin time (PT)/international normalized ratio (INR)
- Rash
- Stevens-Johnson syndrome
- Stomach cramps
- Transient neutropenia and leukopenia
- Urticaria
- Anaphylaxis
- nephrotoxicity
- pseudomembranous colitis
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Furosemide, Aminoglycosides
|
May enhance the nephrotoxic effect
|
|
Oral Anticoagulants (Warfarin, Heparin, Dabigatran, Rivaroxaban, Apixaban, Edoxaban)
|
May enhance the effect
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for allergic reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool, dry place (below 30o C), away from light and moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.