Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Hypertension Age: Adult Condition: Initial |
Dose: Tablet – 20 mg/12.5 mg Frequency: once daily Note: by mouth |
|
Indication: Hypertension Age: Adult Condition: May increase after 2 weeks |
Dose: Tablet – 40 mg/25 mg Frequency: once daily Note: by mouth |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Safety and efficacy not established Note: Not recommended |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal Impairment |
Dose: Not recommended Note: Renal Impairment Creatinine Clearance less than 30 mL/min: Not recommended |
Administration
- Take at same time daily
- Can take with/without food
Side Effect
- Dizziness (3%)
- Headache (1%)
- Fatigue
- Diarrhea (1%)
- Hyperglycemia (1%)
- Hypertriglyceridemia (1%)
- Back pain (1%)
- Bronchitis (1%)
- Flu-like symptoms (1%)
- Pharyngitis (1%)
- Rhinitis (1%)
- Sinusitis (1%)
- URI (1%)
- Chest pain
- Peripheral edema
- Rash
- Hyperuricemia
- Dizziness
- Hyperlipidemia
- Diarrhea
- Hyperuricemia
- Hematuria
- Hyperglycemia
- Upper respiratory infections
- Increased transaminases
- Gastroenteritis
- Dyspepsia
- Arthralgia
- Arthritis
- Myalgia
- Back pain
- Increased CPK
- Hydrochlorothiazide
- Anorexia
- Epigastric distress
- Hypotension
- Orthostatic hypotension
- Photosensitivity
- Anaphylaxis
- Anemia
- Confusion
- Erythema multiforme
- Stevens-Johnson syndrome
- Exfoliative dermatitis including toxic epidermal necrolysis
- Dizziness
- Hypokalemia and/or hypomagnesemia
- Hyperuricemia
- Headache
- Acute renal failure
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Lithium
|
Reduce the renal clearance
|
|
Aliskiren
|
Increased risk of hypotension, hyperkalemia & changes in renal function
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Severe Hepatic & Renal Impairment
|
Can cause drug toxicity
|
|
Cholestasis & Biliary Obstruction
|
Can affect drug metabolism
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool and dry place, protect from light and moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.