Question 1

What is this medicine for, and how does it work?

Accepted Answer

This is an antibiotic combination. It works by interfering with bacterial folic acid synthesis, preventing their growth. It's primarily used to treat urinary tract infections and pneumonia.

Question 2

When and how should this medicine be taken?

Accepted Answer

• Take at regular intervals • Complete full course • Take with adequate fluids

Question 3

When should this medicine not be used?

Accepted Answer

• In late pregnancy • Under 6 weeks

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• Use cautiously in kidney or liver problems • Monitor blood counts regularly • May cause sun sensitivity

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• Not safe in late pregnancy • May cause kernicterus in newborns • Avoid use in late pregnancy

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• Use cautiously in kidney or liver problems • Monitor blood counts regularly • May cause sun sensitivity

Question 7

Is this medicine suitable for children and elderly?

Accepted Answer

• Not safe for newborns under 6 weeks (except for specific treatments)

Question 8

What should be done if a dose is missed?

Accepted Answer

• If you miss a dose, take it as soon as you remember. • However, if it's time for your next dose, skip the missed dose. • Never take two doses in one day. • For twice-daily dosing: If less than 6 hours until your next dose, skip the missed dose. • Take your next dose at the regular time. • If you miss multiple doses, contact your doctor.

Question 9

What should be done in case of an overdose?

Accepted Answer

• Symptoms: Vomiting, rash, anemia. • Treatment: Discontinue drug, hydration, folic acid.

Question 10

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: Allergic reactions, fever, rash, kidney problems, blood disorders • What to do: Report severe skin reactions; Monitor urine output; Complete course; Stay hydrated; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 11

What is Cots used for?

Accepted Answer

Cots (Sulphamethoxazole + Trimethoprim (Co-trimoxazole)) is a pharmaceutical medicine manufactured by Opsonin Pharma Limited in Bangladesh. It is primarily prescribed for Gastrointestinal Tract Infections, Lower Respiratory Tract Infections, Renal Infections, Septicemia, Skin Infection, Upper Respiratory Tract Infection (URTI), Urinary Tract Infection (UTI), Wound Infection.

Question 12

What is the active generic component of Cots?

Accepted Answer

The active ingredient in Cots is Sulphamethoxazole + Trimethoprim (Co-trimoxazole), belonging to the Anti-Diarrhoeal Antimicrobial Drugs drug class.

Question 13

What is the retail price of Cots in Bangladesh?

Accepted Answer

The official retail price of Cots (Suspension) is ৳22.21 in Bangladesh (prices may vary slightly by pack size and authorized pharmacy).

Question 14

What is the recommended dosage for Cots?

Accepted Answer

Standard adult dosage: Tablet – 2 tablet of 480 mg (twice daily). Pediatric dosage: Oral – 8–10 mg TMP/kg/day (every 12 hours). Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 15

Is Cots safe during pregnancy and breastfeeding?

Accepted Answer

Cots is classified under Pregnancy Category "D". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 16

What are the common side effects of Cots?

Accepted Answer

Allergic myocarditis; erythema multiforme; exfoliative dermatitis; angioedema; drug fever; chills; Henoch-Schoenlein purpura; serum sickness-like syndrome; generalised allergic reactions; generalised skin eruptions; phot

Clinical Information	Administration Information
Indication: Acute exacerbations of chronic bronchitis; Acute otitis media; Urinary tract infections; Gastrointestinal infections; Respiratory and urinary tract infections; Susceptible infections Age: Adult	Dose: Tablet – 2 tablet of 480 mg Frequency: twice daily Note: In severe cases, 3 times daily.
Indication: Acute exacerbations of chronic bronchitis; Acute otitis media; Urinary tract infections; Gastrointestinal infections; Respiratory and urinary tract infections; Susceptible infections Age: Adult	Dose: DS Tablet – 1 tablet (960 mg) Frequency: twice daily

Clinical Information	Administration Information
Age: Child	Dose: Oral – 8–10 mg TMP/kg/day Frequency: every 12 hours
Indication: UTI prophylaxis Age: Child	Dose: Oral – 2 mg TMP/kg/day Frequency: every 24 hours

Clinical Information	Administration Information
Age: Adult Condition: Renal impairment	Dose: Not recommended Note: Dosage Recommendation
Age: Adult Condition: Renal impairment	Dose: Half the standard dose Note: Dosage Recommendation

Drug Name	Risk Factors
Ciclosporin	Reduced concentrations in blood
Methotrexate	Increases toxicity

Disease Name	Risk Factors
Severe Hepatic Failure/Liver Damage	Can cause liver failure
Serious Haematological Disorders	Can worsen blood problems

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

Is this medicine suitable for children and elderly?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Renal Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources