Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Folate-deficient megaloblastic anaemia Age: Adult |
Dose: Oral – 5 mg Frequency: daily Duration: 4 months Note: Up to 15 mg daily in malabsorption states. Continued dosing at 5 mg every 1-7 days may be needed in chronic haemolytic states, depending on the diet and rate of haemolysis. |
|
Indication: Prophylaxis of megaloblastic anaemia in pregnancy Age: Adult |
Dose: Oral – 0.2-0.5 mg Frequency: daily |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Folic Acid Deficiency Age: Infants |
Dose: Dosage Form – 15 mcg/kg/day or 50 mcg/day Frequency: once daily |
|
Indication: Folic Acid Deficiency Age: 1-10 years Condition: Initial |
Dose: Dosage Form – 1 mg/day Frequency: once daily |
Administration
- Can take with or without food
- Take daily at same time
Side Effect
- Bronchospasm
- Erythema
- Malaise
- Pruritus
- Rash
- Slight flushing
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Antiepileptics, Oral contraceptives, Anti-TB Drugs (Isoniazid, Rifampicin, Ethambutol, Pyrazinamide), Alcohol, Aminopterin, Methotrexate, Pyrimethamine, Trimethoprim, Sulphonamides
|
May result in decrease in serum folate concentrations
|
|
Phenytoin
|
Decreases serum concentrations
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Untreated Cobalamine Deficiency
|
Can mask vitamin B12 deficiency while allowing neurological damage
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store below 30°C in a dry place, away from light. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.