Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Osteoarthritis Age: Adult |
Dose: Oral – 200 mg Frequency: once daily or in 2 divided doses Note: May increase to 200 mg twice daily, if necessary. |
|
Indication: Rheumatoid arthritis Age: Adult |
Dose: Oral – 100-200 mg Frequency: twice daily |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Juvenile Rheumatoid Arthritis Age: less than 2 years |
Dose: Not applicable Note: Safety and efficacy not established |
|
Indication: Juvenile Rheumatoid Arthritis Age: greater than 2 years |
Dose: by mouth (oral) – 50 mg Frequency: hourly |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Not Specified Note: Relative contraindication to use |
Administration
- Can be taken with or without food
- Take with water
Side Effect
- Headache (10-16%)
- Hypertension (13%)
- Fever (9%)
- Dyspepsia (8.8%)
- Upper respiratory tract infection (URTI) (8.1%)
- Arthralgia (7%)
- Cough (7%)
- Vomiting (6%)
- Diarrhea (5.6%)
- Gastroesophageal reflux (5%)
- Sinusitis (5%)
- Abdominal pain (4.1%)
- Nausea (3.5%)
- Back pain (2.8%)
- Insomnia (2.3%)
- Pharyngitis (2.3%)
- Flatulence (2.2%)
- Rash (2.2%)
- Dizziness (2%)
- Peripheral edema (2%)
- Anemia
- Erythema multiforme
- Exfoliative dermatitis
- Hepatitis
- Jaundice
- Stevens-Johnson syndrome
- Toxic epidermal necrolysis
- Increased serum asparate aminotransferase concentration
- Serious skin reactions such as exfoliative dermatitis
- Stevens-Johnson syndrome
- and toxic epidermal necrolysis
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Fluconazole
|
May increase plasma level
|
|
Lithium
|
May increase serum level
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Severe Hepatic Impairment
|
Can cause liver failure
|
|
Severe Heart Failure
|
Can worsen heart failure symptoms
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.