Question 1

What is this medicine for, and how does it work?

Accepted Answer

This is an antifungal medication from the triazole class. It works by interfering with the formation of the fungal cell wall. It is used to treat serious fungal infections.

Question 2

When and how should this medicine be taken?

Accepted Answer

• Take on empty stomach • Take 1 hour before or 2 hours after meals • Complete prescribed course

Question 3

When should this medicine not be used?

Accepted Answer

• In severe liver disease • In QT prolongation • During pregnancy

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• May cause vision changes • Avoid sun exposure • Use caution in liver problems

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• Use with caution; • Potential risks to fetus; • Use only if benefits outweigh risks

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• May cause vision changes • Avoid sun exposure • Use caution in liver problems

Question 7

Is this medicine suitable for children and elderly?

Accepted Answer

• Effectiveness not established under 12 years

Question 8

What should be done if a dose is missed?

Accepted Answer

• If you miss a dose, take it as soon as you remember. • However, if it's almost time for your next dose, skip the missed dose. • Never take two doses together. • For thrice-daily dosing: If more than 3 hours until your next dose, take the missed dose. • For twice-daily dosing: If more than 6 hours until your next dose, take the missed dose. • Take your next dose at the regular time. • If you're unsure, contact your doctor or pharmacist.

Question 9

What should be done in case of an overdose?

Accepted Answer

• Overdose symptoms: Light sensitivity, dilated pupils, seizures. • Treatment: Supportive and symptomatic care.

Question 10

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: Visual changes (21% - color/brightness changes, blurred vision), fever (up to 21%), skin rash (8-11%), headache (up to 28%), liver problems (up to 15%), nausea (14-16%), vomiting (10-14%) • What to do: Regular eye exams; Report vision changes; Regular liver tests; Avoid sunlight exposure; Take on empty stomach; Report severe reactions; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 11

What is Vorizol 200mg/Vial used for?

Accepted Answer

Vorizol 200mg/Vial (Voriconazole) is a pharmaceutical medicine manufactured by Drug International Ltd. in Bangladesh. It is primarily prescribed for Candidemia, Deep Tissue Candidemia, Fusariosis, Invasive Aspergillosis, Scedosporiosis.

Question 12

What is the active generic component of Vorizol?

Accepted Answer

The active ingredient in Vorizol is Voriconazole, belonging to the Drugs For Subcutaneous And Systemic Mycoses drug class.

Question 13

What is the retail price of Vorizol 200mg/Vial in Bangladesh?

Accepted Answer

The official retail price of Vorizol 200mg/Vial (Injection) is ৳2000.00 in Bangladesh (prices may vary slightly by pack size and authorized pharmacy).

Question 14

What is the recommended dosage for Vorizol?

Accepted Answer

Standard adult dosage: Intravenous – 6 mg/kg (every 12 hours). Pediatric dosage: Not applicable – Safety and efficacy not established. Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 15

Is Vorizol safe during pregnancy and breastfeeding?

Accepted Answer

Vorizol is classified under Pregnancy Category "D". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 16

What are the common side effects of Vorizol?

Accepted Answer

**More than 10%**; Visual changes (photophobia, color changes, increased or decreased visual acuity or blurred vision occur in 21%); **1-10%**; Tachycardia;Hypertension;Hypotension;Vasodilation;Peripheral edema;Fever;Chi

Clinical Information	Administration Information
Indication: Invasive Aspergillosis, Candidemia, Serious Fungal Infections Age: Adult	Dose: Intravenous – 6 mg/kg Frequency: every 12 hours Duration: for first 24 hours Note: loading dose
Indication: Invasive Aspergillosis, Candidemia, Serious Fungal Infections Age: Adult	Dose: Intravenous – 4 mg/kg Frequency: every 12 hours Note: maintenance dose; Hepatic impairment: Mild to moderate (Child-Pugh category A and B): Standard loading dose but maintenance doses should be reduced by 50%

Clinical Information	Administration Information
Age: less than 12 years	Dose: Not applicable – Safety and efficacy not established Note: Safety and efficacy not established
Indication: Invasive Aspergillosis, Candidemia, Serious Fungal Infections Age: greater than 12 years	Dose: Intravenous – 6 mg/kg Frequency: every 12 hours Duration: first 24 hours

Drug Name	Risk Factors
Oral Anticoagulants (Warfarin, Heparin, Dabigatran, Rivaroxaban, Apixaban, Edoxaban)	Increased prothrombin time
Ciclosporin, tacrolimus, long-acting opiates (e.g. oxycodone, methadone), NSAIDs (Ibuprofen, Naproxen, Diclofenac, Celecoxib, Meloxicam, Indomethacin, Piroxicam, Ketorolac) (e.g. ibuprofen, diclofenac), omeprazole, short-acting opiates (e.g. alfentanil, fentanyl)	May increase plasma concentrations

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

Is this medicine suitable for children and elderly?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources