Medicine Overview

Indication

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Adult Dose

Clinical InformationAdministration Information
Indication: Ovarian carcinoma
Age: Adult
Condition: Primary treatment (in combination with cisplatin or carboplatin)
Dose: Intravenous – 135 mg/m2
Frequency: repeated at 3 week intervals
Duration: infused over 24 hours
Note: followed by cisplatin
Indication: Ovarian carcinoma
Age: Adult
Condition: Secondary treatment (as single agent)
Dose: Intravenous – 135 or 175 mg/m2
Frequency: once every 3 weeks
Duration: infused over 3 hours

Child Dose

Clinical InformationAdministration Information
Age: Child
Dose: Safety and efficacy not established
Note: Not recommended
Administration
  • For IV use only
  • Must be diluted before use
Side Effect

Drug Interaction

Drug NameRisk Factors
Cisplatin
Myelosuppression was more profound when given after cisplatin
Carbamazepine, Phenobarbital, Phenytoin, Rifampicin, Rifapentine, Secobarbital
May reduce levels or effects

Disease Interaction

Disease NameRisk Factors
History of Hypersensitivity
Severe allergic reactions possible
Baseline Neutropenia (<1500 cells/mm3)
Increased infection risk

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage

Details coming soon

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.