Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Chronic Hepatitis B Infection
Age: Adults
Condition: Compensated liver disease
Dose: Tablet – 25 mg
Frequency: once daily
Note: Take by mouth with food
Indication: Chronic Hepatitis B Infection
Age: Adults
Condition: Mild (Child-Pugh A) hepatic impairment
Dose: Tablet – 25 mg
Frequency: once daily
Note: No dosage adjustment required; take by mouth with food

Child Dose

Clinical InformationAdministration Information
Indication: Chronic hepatitis B virus infection
Age: 6 years and older
Dose: Oral – 25 mg
Frequency: Once daily

Renal Dose

Clinical InformationAdministration Information
Condition: Mild, moderate, or severe renal impairment
Dose: No dosage adjustment required
Note: No dosage adjustment required
Condition: End Stage Renal Disease (Creatinine Clearance less than 15 mL/min)
Dose: Use not recommended
Note: Use not recommended
Administration
  • Take with food
  • Take at regular intervals
Side Effect

Drug Interaction

Drug NameRisk Factors
Carbamazepine, oxcarbazepine, phenobarbital, phenytoin, rifabutin, rifampin, rifapentine, St John's wort
Decreased absorption and plasma concentrations, which may lead to loss of therapeutic effect
P-gp and BCRP inhibitors
May increase absorption and plasma concentration

Disease Interaction

Disease NameRisk Factors
Severe kidney disease
Can worsen kidney function

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store below 86°F (30°C). Keep in its original container. Keep the container tightly closed.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.