Medicine Overview

Indication
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Adult Dose
Clinical InformationAdministration Information
Indication: Diabetes Mellitus
Age: Adult
Condition: Typical daily insulin requirements
Dose: Subcutaneous – 0.5-1 unit/kg
Note: Combination rapid-onset (faster than regular insulin) and intermediate-acting insulins in fixed dose. Dose regimen varies among patients depending on metabolic needs.
Indication: Diabetes Mellitus
Age: Adult
Condition: Initial dose
Dose: Subcutaneous – 10 units
Frequency: with the largest meal of the day
Note: Dose adjustments may be made on a weekly basis according to blood glucose levels. Dose should not be increased if there is hypoglycaemic episode (less than 70 mg/dl) during a 3-day period.

Child Dose
Clinical InformationAdministration Information
Age: Child
Dose: Safety and efficacy not established
Note: Not recommended

Renal Dose
Clinical InformationAdministration Information
Condition: Renal impairment
Dose: Not specified – Dose adjustments may be required
Note: Renal impairment: Dose adjustments may be required.
Administration
  • Give SC injection
  • Inject before meals
Side Effect

Drug Interaction
Drug NameRisk Factors
Oral antidiabetic agents, ACE Inhibitors (Captopril, Enalapril, Lisinopril, Ramipril, Benazepril, Fosinopril, Quinapril, Perindopril), disopyramide, fibrates, fluoxetine, MAOIs (Phenelzine, Tranylcypromine, Selegiline, Moclobemide), propoxyphene, salicylates, somatostatin analog (e.g., octreotide), Sulfonamide Antibiotics (Sulfamethoxazole, Sulfisoxazole, Sulfadiazine)
Effects may be increased
Corticosteroids (Prednisone, Prednisolone, Methylprednisolone, Dexamethasone, Hydrocortisone), niacin, danazol, diuretics, sympathomimetic agents, isoniazid, phenothiazine derivatives, somatropin, thyroid hormones, oral contraceptives, lithium
Effects may be decreased

Disease Interaction
Disease NameRisk Factors
Hypoglycemia
Risk of dangerously low blood sugar

Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at 2-8° C in a refrigerator. Do not freeze. In case of insulin for recent use need not be refrigerated, try to keep it in a cool place and keep away from heat and light. The insulin in use can be kept under the room temperature for a month.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.