Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Adult |
Dose: Injection – 0.5-20 mg Frequency: daily, either as a single intravenous/intramuscular injection or by intravenous infusion |
|
Indication: Cerebral Edema |
Dose: Injection – 10 mg Frequency: intravenous once, then 4 mg intramuscular every 6 hours Note: Until clinical improvement is observed; may be reduced after 2-4 days and gradually discontinued over 5-7 days |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Airway Edema |
Dose: Injection – 0.5-2 mg/kg/day Frequency: intravenous or intramuscular divided every 6 hours Note: starting 24 hours before extubation and continued for 4-6 doses afterward |
|
Indication: Croup |
Dose: Injection – 0.6 mg/kg Frequency: intravenous or intramuscular once Note: not to exceed 16 mg |
Administration
- Take with food
- Follow prescribed schedule
Side Effect
- Acne
- Adrenal suppression
- Arrhythmia
- Bradycardia
- Cardiac arrest
- Cataracts
- Change in spermatogenesis
- Delayed wound healing
- Depression
- Diabetes mellitus
- Diaphoresis
- Emotional instability
- Erythema
- Euphoria
- Exophthalmos
- GI perforation
- Glaucoma
- Glucose intolerance
- Glucosuria
- Hepatomegaly
- Hypokalemic alkalosis
- Increased intracranial pressure
- Increased transaminases
- Insomnia
- Kaposi's sarcoma
- Menstrual irregularity
- Moon face
- Myopathy
- Neuritis
- Osteoporosis
- Peptic ulcer
- Perianal pruritus
- Petechia
- Perianal pruritus
- Pituitary adrenal axis suppression
- Pseudotumor cerebri (on withdrawal)
- Psychosis
- Pulmonary edema
- Rash
- Seizure
- Spermatogenesis altered (increased or decreased)
- Ulcerative esophagitis
- Urticaria
- Vertigo
- Weight gain
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Amphotericin B, loop diuretics (Furosemide, Bumetanide, Ethacrynic acid, Torsemide)
|
Increased risk of hypokalemia
|
|
Isoniazid, Salicylates, Vaccines, Toxoids (Vaccine preparations)
|
Reduces efficacy
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Systemic Fungal Infections
|
Can worsen fungal infection
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Tablet: Store in a cool & dry place, protected from light & moisture.
Injection: Store below 30° C, protected from light.Do not freeze. Keep medicines out of the reach of children
Injection: Store below 30° C, protected from light.Do not freeze. Keep medicines out of the reach of children
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.