Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Corticosteroid-responsive Dermatoses |
Dose: Cream/Ointment – Thin layer Frequency: twice daily Note: Rub in gently and completely; not to exceed 50 g/week |
|
Indication: Scalp Psoriasis |
Dose: Shampoo – Thin film Frequency: once daily Duration: leave in place for 15 minutes Note: Apply to dry scalp; add water, lather, and then rinse thoroughly |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: less than 12 years |
Dose: Not established Note: Safety and efficacy not established |
|
Indication: Corticosteroid-responsive Dermatoses Age: greater than 12 years |
Dose: Cream/Ointment – Apply a thin layer Frequency: twice daily Note: Rub in gently and completely; not to exceed 50 g/week |
Administration
- Clean area before use
- Apply thin layer
Side Effect
- Perioral dermatitis
- striae esp in flexures
- Dermal and epidermal atrophy esp on the face
- steroid purpura
- Burning
- Cracking/fissuring of the skin
- Erythema
- Folliculitis
- Irritation
- Numbness
- Pruritus
- Stinging
- Hypopigmentation (high potency topical steroids)
- Prolonged usage of large amount of clobetasol propionate can lead to sufficient systemic levels to produce adrenal suppression
- Cushing's syndrome
- diabetes and hypertension
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
CYP3A4 inhibitors (e.g. ritonavir, itraconazole)
|
Increased systemic exposure
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Long-term Treatment Of Ulcerative Conditions
|
Can delay healing
|
|
Rosacea
|
Can worsen skin condition
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature, protected from light and moisture. Do not freeze. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.