Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Thromboembolic disorders Age: Adult |
Dose: Intravenous – Initially, 500 ml of a 10% solution in sodium chloride 0.9% Frequency: Infused over 4-6 hours, followed by 500 ml infused over 4-6 hours on the next and subsequent alternate days Duration: Not more than 10 days Note: As dextran 40 |
|
Indication: Prophylaxis of postoperative thromboembolic disorders Age: Adult |
Dose: Intravenous – 500 ml of a 10% solution in sodium chloride 0.9% Frequency: Infused over 4-6 hours during or at the end of surgery; dose may be repeated the following day and continued on alternate days Duration: Up to 10 days in high-risk patient Note: As dextran 40 |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Thromboembolic disorders Age: Child Condition: Infants |
Dose: Intravenous – Up to 5 ml/kg Note: As dextran 40 |
|
Indication: Thromboembolic disorders Age: Child |
Dose: Intravenous – Up to 10 ml/kg Note: As dextran 40 |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Dose: Note: Extreme caution |
Administration
- For hospital use only
- Must be administered by professional
Side Effect
- Congestive heart failure
- Mild hypotension
- Tightness of chest
- Thrombocytopenia
- Anaphylaxis
- Injection site infection/phlebitis
- Acute renal failure
- Acidosis (if NaCl soln used)
- Pulmonary edema
- Wheezing
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Phenytoin, Carbamazepine
|
Enzyme inducers
|
|
Cimetidine
|
Enzyme inhibitor
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Severe Renal Disease
|
Can worsen kidney function
|
|
Cardiac Decompensation
|
Risk of fluid overload
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at 25°C.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.