Medicine Overview

Indication

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Adult Dose

Clinical InformationAdministration Information
Indication: Thromboembolic disorders
Age: Adult
Dose: Intravenous – Initially, 500 ml of a 10% solution in sodium chloride 0.9%
Frequency: Infused over 4-6 hours, followed by 500 ml infused over 4-6 hours on the next and subsequent alternate days
Duration: Not more than 10 days
Note: As dextran 40
Indication: Prophylaxis of postoperative thromboembolic disorders
Age: Adult
Dose: Intravenous – 500 ml of a 10% solution in sodium chloride 0.9%
Frequency: Infused over 4-6 hours during or at the end of surgery; dose may be repeated the following day and continued on alternate days
Duration: Up to 10 days in high-risk patient
Note: As dextran 40

Child Dose

Clinical InformationAdministration Information
Indication: Thromboembolic disorders
Age: Child
Condition: Infants
Dose: Intravenous – Up to 5 ml/kg
Note: As dextran 40
Indication: Thromboembolic disorders
Age: Child
Dose: Intravenous – Up to 10 ml/kg
Note: As dextran 40

Renal Dose

Clinical InformationAdministration Information
Condition: Renal impairment
Dose: Dose:
Note: Extreme caution
Administration
  • For hospital use only
  • Must be administered by professional
Side Effect

Drug Interaction

Drug NameRisk Factors
Phenytoin, Carbamazepine
Enzyme inducers
Cimetidine
Enzyme inhibitor

Disease Interaction

Disease NameRisk Factors
Severe Renal Disease
Can worsen kidney function
Cardiac Decompensation
Risk of fluid overload

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at 25°C.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.