Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Vitamin K deficiency due to drugs or malabsorption Age: Adult |
Dose: Oral – 10-40 mg Frequency: daily |
|
Indication: Over-anticoagulation Age: Adult |
Dose: Oral – Up to 5 mg Note: Dose depends on International Normalized Ratio and degree of haemorrhage. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Prophylaxis of vitamin K deficiency bleeding Age: Neonate |
Dose: Intramuscular Injection – 0.5-1 mg Note: given as a single dose |
|
Indication: Prophylaxis of vitamin K deficiency bleeding Age: Neonate |
Dose: Oral – 2 mg Note: followed by a second dose of 2 mg after 4-7 days |
Administration
- May be taken with or without food
- Take with water
Side Effect
- Anaphylaxis
- dyspnoea
- cyanosis
- pain
- swelling
- phloebitis at the Injection site
- diaphoresis
- dizziness
- hypotension (rare)
- allergic reactions after SC and IM inj
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Oral Anticoagulants (Warfarin, Heparin, Dabigatran, Rivaroxaban, Apixaban, Edoxaban)
|
Decreased effect
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for general reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.