Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Ancylostoma, Ascariasis, Hookworm, Trichostrongylus, Enterobius (Pinworm) |
Dose: Oral – 400 mg Frequency: once daily Duration: single dose |
|
Indication: Tapeworm infections Age: Adult |
Dose: Oral – 400 mg Frequency: once daily Duration: 3 consecutive days Note: Take on an empty stomach. Max: 400 mg daily; 1200 mg for 3 days. If patient is not cured after 3 weeks, a second course of treatment is needed. In cases of Hymenolepis nana infestations, retreatment in 10-21 days is recommended. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: by mouth (oral) – 15 mg/kg/day Frequency: every 12 hours Note: maximum 800 mg/day |
|
Indication: Ascariasis, Enterobiasis, Trichuriasis, Hookworm infections Age: Child: 1-2 years |
Dose: suspension – 5 ml (200 mg) Frequency: single dose Note: maximum 200 mg |
Administration
- Take with fatty meal
- Complete full course
Side Effect
- Headache
- Neurocysticercosis (11%)
- Hydatid disease (1.3%)
- Abnormal LFT
- Hydatid disease (15.6%)
- Neurocysticercosis (Less than 1%)
- Abdominal pain
- Hydatid disease (6%)
- Nausea/vomiting
- Hydatid disease (3.7%)
- Neurocysticercosis (6.2%)
- Dizziness/vertigo
- Hydatid disease (1.2%)
- Neurocysticercosis (Less than 1%)
- Increased intracranial pressure
- Neurocysticercosis (1%)
- Meningeal signs
- Neurocysticercosis (1%)
- Alopecia (reversible)
- Hydatid disease (1.6%)
- Neurocysticercosis (Less than 1%)
- Fever
- Hydatid disease (1%)
- Rash
- Urticaria
- Agranulocytosis
- Aplastic anemia
- Bone marrow suppression
- Granulocytopenia
- Pancytopenia
- Thrombocytopenia
- Hepatitis
- Acute liver failure
- Acute renal failure
- Bone marrow depression
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Dexamethasone, Praziquantel, Cimetidine
|
Increased serum concentrations
|
|
Aminoquinoline (Antimalarials (Chloroquine, Hydroxychloroquine, Primaquine, Mefloquine)), Carbamazepine, Phenobarbital, Phenytoin
|
Decreased serum concentrations
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Liver Impairment
|
Can worsen liver function
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep in a dry place, away from light and heat. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.