Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Osteoarthritis
Age: Adult
Dose: Oral Tablet – 600-1000 mg
Frequency: twice daily
Note: Dose adjusted according to response. Maximum: 1200 mg/day. Hepatic impairment: Dose adjustment not necessary.
Indication: Rheumatoid arthritis
Age: Adult
Dose: Oral Tablet – 600-1000 mg
Frequency: twice daily
Note: Dose adjusted according to response. Maximum: 1200 mg/day. Hepatic impairment: Dose adjustment not necessary.

Child Dose

Clinical InformationAdministration Information
Indication: Juvenile Rheumatoid Arthritis
Age: less than 6 years
Dose: Safety and efficacy not established
Note: Safety and efficacy not established
Indication: Juvenile Rheumatoid Arthritis
Age: 6-16 years
Dose: Extended release tablet – 400 mg
Frequency: once daily
Note: by mouth (oral)

Renal Dose

Clinical InformationAdministration Information
Condition: Mild-to-moderate renal impairment
Dose: Dosage Form – Dose adjustment not necessary
Note: Dose adjustment not necessary
Condition: Severe renal impairment
Dose: Dosage Form – Not recommended
Note: Not recommended
Administration
  • Take with food
  • Take with water
Side Effect

Drug Interaction

Drug NameRisk Factors
Warfarin, Lithium, Methotrexate, Digoxin, Cyclosporin, Aspirin
Increased effect
Some diuretics and β-blockers
Reduced effect

Disease Interaction

Disease NameRisk Factors
Peptic Ulcer
Risk of bleeding and perforation

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Do not store above 30°C. Keep away from light and out of the reach of children.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.