Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Allergic Rhinitis, Urticaria |
Dose: Tablet – 10 mg Frequency: once daily Note: not to exceed 10 mg every day |
|
Indication: Allergic Rhinitis, Urticaria |
Dose: Tablet – 5 mg Frequency: 12 hourly Note: not to exceed 10 mg every day |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Allergic Rhinitis Age: less than 2 years |
Dose: Oral Tablet Note: Safety and efficacy not established |
|
Indication: Allergic Rhinitis Age: 2-6 years |
Dose: Oral Tablet – 5 mg Frequency: once daily Note: by mouth (oral) |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Adult Condition: Renal impairment (Glomerular Filtration Rate less than 30 mL/minute) |
Dose: by mouth – 10 mg Frequency: every other day |
|
Age: 2-6 years Condition: Renal impairment |
Dose: by mouth – 5 mg Frequency: every other day |
Administration
- Can take with/without food
- Regular timing
Side Effect
- Somnolence (8%)
- Drowsiness (8%)
- Nervousness (4%)
- Fatigue (3-4%)
- Dry mouth (3%)
- Hyperkinesia (3%)
- Conjunctivitis (2%)
- Dysphonia (2%)
- Malaise (2%)
- URTI (2%)
- Autonomic nervous system Altered lacrimation
- altered salivation
- flushing
- hypoesthesia
- impotence
- increased sweating
- thirst
- Cardiovascular HTN
- hypotension
- palpitations
- supraventricular tachyarrhythmias
- syncope
- tachycardia
- CNS Blepharospasm
- dizziness
- dysphonia
- hypertonia
- migraine
- paresthesia
- tremor
- vertigo GI Altered taste
- anorexia
- constipation
- diarrhea
- dyspepsia
- flatulence
- gastritis
- hiccup
- increased appetite
- loose stools
- nausea
- vomiting
- Musculoskeletal Arthralgia
- myalgia
- Psychiatric Agitation
- amnesia
- anxiety
- confusion
- decreased libido
- depression
- impaired concentration
- insomnia
- irritability
- paroniria
- Reproductive Breast pain
- dysmenorrhea
- menorrhagia
- vaginitis
- Respiratory Bronchitis
- bronchospasm
- coughing
- dyspnea
- hemoptysis
- laryngitis
- nasal dryness
- sinusitis
- sneezing
- Skin Dermatitis
- dry hair
- dry skin
- photosensitivity reaction
- pruritus
- purpura
- urticaria
- Urinary Altered micturition
- urinary discoloration
- urinary incontinence
- urinary retention
- Angioneurotic edema
- Asthenia
- Back pain
- Blurred vision
- Chest pain
- Earache
- Eye pain
- Fever
- Leg cramps
- Malaise Rigors
- Tinnitus
- Weight gain
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
CYP3A4 and/or CYP2D6 inhibitors (e.g. cimetidine, erythromycin, ketoconazole, clarithromycin, quinidine, fluconazole, fluoxetine)
|
May increase plasma concentrations
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for general reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep in a dry place away from light and heat. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.