Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Parkinsonism and drug-induced extrapyramidal syndrome
Age: Adult
Dose: Oral as hydrochloride – Initially, 2.5 mg
Frequency: three times daily
Note: increased gradually by 2.5-5 mg every 2-3 days if required
Indication: Parkinsonism and drug-induced extrapyramidal syndrome
Age: Adult
Dose: Oral as hydrochloride – 10-30 mg/day
Frequency: in 3-4 divided doses
Note: Maintenance dose. Up to 60 mg daily may be required in some cases.

Child Dose

Clinical InformationAdministration Information
Indication: Dystonia
Age: 7-12 years
Dose: Oral – 1.25 mg
Frequency: three times daily
Indication: Dystonia
Age: 12-18 years
Dose: Oral – 2.5 mg
Frequency: three times daily
Administration
  • Take with water
  • Space doses evenly throughout day
Side Effect

Drug Interaction

Drug NameRisk Factors
Paroxetine
Increased plasma concentrations
MAOIs (Phenelzine, Tranylcypromine, Selegiline, Moclobemide), Other anticholinergic drugs
Enhanced anticholinergic action

Disease Interaction

Disease NameRisk Factors
Urinary Outflow Obstruction
Can cause complete urinary retention
Prostatic Hypertrophy
Worsens urinary symptoms

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Protect from light and moisture, store below 25°C. Keep out of the reach of children.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.