Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Hypercholesterolemia, Mixed dyslipidemia, Hypertriglyceridemia Age: Adult |
Dose: Tablet – 40-160 mg Frequency: once daily Note: Hepatic impairment: Contraindicated. |
|
Indication: Hypercholesterolemia, Mixed dyslipidemia, Hypertriglyceridemia Age: Adult |
Dose: Capsule – 200 mg Frequency: once daily Note: Hepatic impairment: Contraindicated. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Tablet – Safety and efficacy not established |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Mild to Moderate renal impairment |
Dose: Initial: lower dose Note: Renal impairment Mild-Moderate: Initial: lower dose |
|
Condition: Severe renal impairment |
Dose: Contraindicated Note: Renal impairment Severe: contraindicated |
Administration
- Take with food
- Take with evening meal
Side Effect
- Abdominal pain (4.6%)
- Back pain (3.4%)
- Increased AST (3.4%)
- Headache (3.2%)
- Increased ALT (3%)
- Increased CPK (3%)
- Nausea (2.3%)
- Constipation (2.1%)
- Hepatitis
- cholecystitis
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Bile Acid Sequestrants (Cholestyramine, Colestipol, Colesevelam) (e.g. colestyramine)
|
Decreased absorption
|
|
Ciclosporin
|
May increase risk of nephrotoxicity
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Severe Hepatic Impairment
|
Can worsen liver function
|
|
Severe Renal Impairment
|
Can worsen kidney function
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Do not store above 30°C. Keep away from light and out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.