Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Rheumatic disorders Age: Adult Condition: Initial |
Dose: Dose – 20 mg/day Frequency: once daily Note: as a single dose |
|
Indication: Rheumatic disorders Age: Adult Condition: Maintenance |
Dose: Dose – 10-30 mg Frequency: once daily or in divided doses Note: single or divided doses |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Juvenile idiopathic arthritis Age: Child: greater than 6 years |
Dose: Dosage Form – 5 mg Frequency: once daily |
|
Indication: Juvenile idiopathic arthritis Age: Child: greater than 6 years |
Dose: Dosage Form – 10 mg Frequency: once daily |
Administration
- Take with food
- Take with full glass of water
Side Effect
- Indigestion (3.8-9.5% )
- Upper respiratory infection (up to 8.3% )
- Headache (2.4-8.3% )
- Diarrhea (1.9-7.8% )
- Nausea (2.4-7.2% )
- Abdominal pain (1.9-4.7%)
- Edema (0.6- 4.5%)
- Anemia (up to 4.1% )
- Dizziness (1.1-3.8% )
- Constipation (0.8-2.6% )
- Vomiting
- Fever
- Angina (Less than 2% )
- Congestive heart failure (Less than 2% )
- Hypertension (Less than 2% )
- Myocardial infarction (Less than 2% )
- Gastrointestinal hemorrhage (Less than 2% )
- Gastrointestinal perforation
- gastrointestinal ulcer (Less than 2% )
- Inflammatory disorder of digestive tract (Less than 2% )
- Decreased platelet aggregation
- purpuric disorder (Less than 2% )
- Hepatitis (Less than 2% )
- Erythema multiforme
- erythroderma
- Stevens-Johnson syndrome
- Toxic epidermal necrolysis
- Jaundice
- liver failure
- Anaphylactoid reaction
- Immune hypersensitivity reaction
- Cerebrovascular accident
- Interstitial nephritis
- renal failure
- Asthma
- bronchospasm
- Angioedema
- Tinnitus
- hearing loss
- Thrombocytopaenia and acute nephropathy
- Toxic epidermal necrolysis and Stevens-Johnson syndrome
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Anti-platelets, SSRIs
|
Increased risk of GI bleeding
|
|
Cardiac medications
|
May exacerbate cardiac failure, reduce GFR, increase plasma glycoside levels
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Hypersensitivity, Asthma reactions to NSAIDs
|
Can cause severe allergic reactions
|
|
GI Ulceration, Bleeding, Crohn's Disease, GI Cancers
|
Can worsen GI bleeding and ulceration
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.