Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Hypertension |
Dose: Oral Tablet – 16-32 mg candesartan/12.5-25 mg hydrochlorothiazide Frequency: once daily |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: Tablet – No approved pediatric dosage available Note: Not recommended for children |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Mild to moderate renal impairment (creatinine clearance between 30-80 mL/min/1.73m2 Body Surface Area) |
Dose: Not specified – Not specified Note: A dose titration is recommended. |
|
Condition: Severe renal impairment (creatinine clearance less than 30 mL/min/1.73 m2 Body Surface Area) |
Dose: Not specified – Not specified Note: This should not be used in patients with severe renal impairment. |
Administration
- Can be taken with or without food
- Take at same time daily
Side Effect
- Headache (3%)
- Dizziness (3%)
- Upper respiratory tract infection (URTI) (4%)
- Back pain (3%)
- Dizziness
- headache
- vertigo
- back pain
- upper resp tract infections
- pharyngitis
- rhinitis
- hypotension
- hyperkalaemia
- increased serum creatinineeatinine
- Anorexia
- Epigastric distress
- Hypotension
- Orthostatic hypotension
- Photosensitivity
- Anaphylaxis
- Anemia
- Confusion
- Erythema multiforme
- Stevens-Johnson syndrome
- Exfoliative dermatitis including toxic epidermal necrolysis
- Dizziness
- Headache
- Hyperuricemia
- Hypokalemia and/or hypomagnesemia
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
NSAIDs (Ibuprofen, Naproxen, Diclofenac, Celecoxib, Meloxicam, Indomethacin, Piroxicam, Ketorolac)
|
May reduce antihypertensive effect and deteriorate renal function
|
|
Lithium
|
May increase serum concentration
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for general drug reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.