Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Osteoarthritis of Knee Age: Adult |
Dose: Intra-articular Injection – 20 mg (2 mL) Frequency: once weekly Duration: 3-5 weeks Note: Indicated for treatment of pain in osteoarthritis of the knee |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Tablet – Safety and efficacy not established Note: Safety and efficacy not established |
Administration
- Must be administered by healthcare professional
- For ophthalmic use only
Side Effect
- Arthralgia (25%)
- Tenderness (61-92%)
- Swelling (81-91%)
- Firmness (88-89%)
- Bruising (52-87%)
- Pruritus (25-36%)
- Skin discoloration (33-78%)
- Firmness (86-89%)
- Lumps/bumps (56-83%)
- Increased blood pressure (4%)
- Fatigue (1%)
- Nausea (Less than 2%)
- Injection site pain (3%)
- Paresthesia (1%)
- Tendonitis (2%)
- Limb pain (1%)
- Tendonitis (2%)
- Joint effusion (2%)
- Angioedema
- Arthritis
- Herpetic eruptions
- Thrombocytopenia
- Peripheral edema
- Vasovagal reaction
- Hives
- Gait disturbances
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Quaternary Amine Bactericides (Specific disinfectant agents), Disinfectants
|
Sodium hyaluronate is precipitated
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Hypersensitivity to Sodium Hyaluronate or Avian Proteins
|
Can cause severe allergic reactions
|
|
Skin diseases or infections at injection site
|
Can worsen existing skin conditions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Hyronate injection should be stored in a cool (below 25° C) and dry place and protected from light. Protect from freezing.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.