Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Lower Respiratory Tract, Skin/Skin Structure, & Gynecologic Infections Condition: Mild to moderate |
Dose: Intravenous – 500-750 mg Frequency: every 12 hours |
|
Indication: Intra-abdominal Infections Condition: Mild to moderate |
Dose: Intravenous – 250-500 mg Frequency: every 6 hours |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Intravenous – 60–100 mg/kg/day Frequency: every 6 hours |
|
Age: Child Condition: Age greater than or equal to 12 years |
Dose: Intramuscular – 60–100 mg/kg/day Frequency: every 6 hours |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment: Creatinine Clearance 31-70 ml/min |
Dose: 500 mg Frequency: every 6-8 hours |
|
Condition: Renal impairment: Creatinine Clearance 21-30 ml/min |
Dose: 500 mg Frequency: every 8-12 hours |
Administration
- For hospital use only
- Must be given by IV
Side Effect
- Phlebitis (2-5%)
- Eosinophilia (4%)
- Miscellaneous dermatologic effects (Less than 3%)
- Potentially false-positive Coombs test (2%)
- Miscellaneous hematologic effects (Less than 2%)
- Transient increase in blood urea nitrogen (BUN) or serum creatinineeatinine (Less than 2%)
- Seizures (1.5%)
- Nausea
- diarrhea
- vomiting (1-2%)
- Abnormal urinalysis
- Agitation
- Anaphylaxis
- Anemia
- Confusion (acute)
- Dizziness
- Dyskinesia
- Emergence of resistant strains of Pseudomonas aeruginosa
- Fever
- Hypersensitivity
- Hypotension
- Elevated liver function test (LFT) results
- Increased prothrombin time (PT)
- Neutropenia (including agranulocytosis)
- Palpitations
- Pruritus
- Pseudomembranous colitis
- Stevens-Johnson syndrome
- toxic epidermal necrolysis
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Probenecid
|
May increase the half-life of cilastatin
|
|
Ganciclovir
|
Increased risk of generalized seizures
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for allergic reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.