Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Type 1 diabetes mellitus Age: Adult Condition: Subcutaneous |
Dose: Subcutaneous – Approximately one third of the total daily insulin requirements Note: Rapid-acting or short-acting, premeal insulin should be used to satisfy the remainder of the daily insulin requirements |
|
Indication: Type 1 diabetes mellitus Age: Adult Condition: Subcutaneous, Maintenance |
Dose: Subcutaneous – 0.5-1 unit/kg/day Frequency: divided doses Note: Usual daily maintenance range |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Type 1 Diabetes Mellitus Age: less than 3 years |
Dose: Subcutaneous Injection – Rapid-acting human insulin analogue Note: Safety and efficacy not established |
|
Indication: Type 1 Diabetes Mellitus Age: greater than 3 years Condition: growth spurts |
Dose: Subcutaneous Injection – 0.8-1.2 units/kg/day Frequency: daily |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Not specified – Dose reduction may be needed Note: Renal impairment: Dose reduction may be needed. |
Administration
- Inject within 15min of meal
- Rotate injection sites
Side Effect
- Hypoglycaemia
- hypokalemia
- oedema
- pruritus
- pulpitation
- nausea
- rash
- hypersensitivity reactions
- lipoatropy or lipohypertrophy with SC Inj
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Oral antidiabetic agents, ACE Inhibitors (Captopril, Enalapril, Lisinopril, Ramipril, Benazepril, Fosinopril, Quinapril, Perindopril), Disopyramide, Fibrates, Fluoxetine, MAOIs (Phenelzine, Tranylcypromine, Selegiline, Moclobemide), Propoxyphene, Salicylates, Somatostatin analog, Sulfonamide Antibiotics (Sulfamethoxazole, Sulfisoxazole, Sulfadiazine)
|
Effects may be increased
|
|
Corticosteroids (Prednisone, Prednisolone, Methylprednisolone, Dexamethasone, Hydrocortisone), Niacin, Danazol, Diuretics, Sympathomimetic agents, Isoniazid, Phenothiazine derivatives, Somatropin, Thyroid hormones, Oral contraceptives, Lithium
|
Effects may be decreased
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Hypoglycaemia
|
Can dangerously lower blood sugar
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at 2°C - 8°C in a refrigerator. Do not freeze. In case of insulin for recent use need not be refrigerated, try to keep it in a cool place and keep away from heat and light. The insulin in use can be kept under the room temperature for a month.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.