Question 1

What is this medicine for, and how does it work?

Accepted Answer

This is an opioid pain medicine. It works by changing pain signals in the brain and nervous system. It's primarily used to treat moderate to severe pain.

Question 2

When and how should this medicine be taken?

Accepted Answer

• Can be taken with or without food • Take at regular intervals as prescribed • Do not crush or chew extended-release tablets

Question 3

When should this medicine not be used?

Accepted Answer

• In respiratory depression • In head injury

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• Risk of respiratory depression - use with extreme caution • Not recommended for opioid-dependent patients • Use reduced doses with CNS depressants • Avoid use with MAO inhibitors • Use carefully in head injury or increased intracranial pressure • Risk of addiction - monitor for abuse • Can cause seizures - use caution in epilepsy

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• Use with caution; • May cause neonatal withdrawal syndrome; • Use only if clearly needed

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• Risk of respiratory depression - use with extreme caution • Not recommended for opioid-dependent patients • Use reduced doses with CNS depressants • Avoid use with MAO inhibitors • Use carefully in head injury or increased intracranial pressure • Risk of addiction - monitor for abuse • Can cause seizures - use caution in epilepsy

Question 7

Is this medicine suitable for children and elderly?

Accepted Answer

• Children (1 year+): 1-2 mg/kg body weight • Not for children under 14 years (suppository) • SR capsules not studied in children

Question 8

What should be done if a dose is missed?

Accepted Answer

• If you miss a dose, take it as soon as you remember. • However, if it's almost time for your next dose, skip the missed dose. • Never take two doses together. • For once-daily dosing: If you remember on the same day, take the dose. • For twice-daily dosing: If more than 6 hours until your next dose, take the missed dose. • Take your next dose at the regular time. • If you miss multiple doses, contact your doctor.

Question 9

What should be done in case of an overdose?

Accepted Answer

• Symptoms: CNS depression, miosis, respiratory depression. • Treatment: Naloxone, airway protection.

Question 10

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: Constipation, nausea, dizziness, headache, drowsiness • What to do: Don't drive; Avoid alcohol; Report severe reactions; Take with food; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 11

What is Kadol 50mg used for?

Accepted Answer

Kadol 50mg (Tramadol Hydrochloride) is a pharmaceutical medicine manufactured by Kemiko Pharmaceuticals Ltd. in Bangladesh. It is primarily prescribed for Moderate to Severe Pain, Postoperative Pain.

Question 12

What is the active generic component of Kadol?

Accepted Answer

The active ingredient in Kadol is Tramadol Hydrochloride, belonging to the Opioid Analgesics drug class.

Question 13

What is the retail price of Kadol 50mg in Bangladesh?

Accepted Answer

The official retail price of Kadol 50mg (Capsule) is ৳8.02 in Bangladesh (prices may vary slightly by pack size and authorized pharmacy).

Question 14

What is the recommended dosage for Kadol?

Accepted Answer

Standard adult dosage: Oral – 25 mg by mouth every morning initially (once daily). Pediatric dosage: Tablet – Dosage not established. Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 15

Is Kadol safe during pregnancy and breastfeeding?

Accepted Answer

Kadol is classified under Pregnancy Category "Not Assigned". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 16

What are the common side effects of Kadol?

Accepted Answer

**More than 10%**; Constipation (24-46%);Nausea (24-40%);Dizziness (10-33%);Vertigo (26-33%);Headache (18-32%);Somnolence (7-25%);Vomiting (9-17%);Agitation (7-14%);Anxiety (7-14%);Emotional lability (7-14%);Euphoria (7-

Clinical Information	Administration Information
Indication: Moderate to severe pain Age: Adult Condition: Chronic pain, Immediate release	Dose: Oral – 25 mg by mouth every morning initially Frequency: once daily Note: Dosage can be increased by 25-50 mg/day every 3 days up to 50-100 mg by mouth every 4-6 hours as needed; not to exceed 400 mg/day.
Indication: Moderate to severe pain Age: Adult Condition: Acute pain, Immediate release	Dose: Oral – 50-100 mg by mouth Frequency: every 4-6 hours as needed Note: Not to exceed 400 mg/day.

Clinical Information	Administration Information
Indication: Moderate-to-Severe Pain Age: less than 17 years Condition: Immediate release	Dose: Tablet – Dosage not established Note: Safety and efficacy not established
Indication: Moderate-to-Severe Pain Age: greater than 17 years Condition: Acute, Immediate release	Dose: Tablet – 50-100 mg Frequency: every 4-6 hours as needed Note: by mouth (oral); not to exceed 400 mg/day

Clinical Information	Administration Information
Condition: Renal impairment with Creatinine Clearance 10-30 ml/min	Dose: Dosage Form with Dose – Dosage Recommendation Frequency: every 12 hours Note: Increase dosing interval to 12 hourly
Condition: Renal impairment with Creatinine Clearance less than 10 ml/min	Dose: Dosage Form with Dose – Dosage Recommendation Note: Contraindicated

Drug Name	Risk Factors
SSRI, serotonin-norepinephrine reuptake inhibitors (SNRI), TCA, other seizure threshold lowering drugs (e.g. bupropion, mirtazapine, tetrahydrocannabinol)	Increased risk of convulsions or serotonin syndrome
Carbamazepine	Decreased serum concentrations

Disease Name	Risk Factors
Suicidal Tendency/Acute Alcoholism	Risk of overdose
Head Injuries/Raised Intracranial Pressure	Can worsen brain condition

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

Is this medicine suitable for children and elderly?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Renal Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources