Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Advanced or locally advanced breast cancer ; Adjuvant therapy for postmenopausal women with hormone receptor positive early breast cancer Age: Adult |
Dose: Oral – 2.5 mg Frequency: once daily |
|
Indication: Advanced or locally advanced breast cancer ; Adjuvant therapy for postmenopausal women with hormone receptor positive early breast cancer Age: Adult Condition: Hepatic impairment: cirrhosis and severe hepatic impairment |
Dose: Oral – 2.5 mg Frequency: on alternate days Note: Reduce dose by 50% in patients with cirrhosis and severe hepatic impairment; recommended dose: 2.5 mg on alternate days. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: Not applicable – No approved pediatric dosage available Note: No approved pediatric dosage available |
Administration
- Can be taken with or without food
- Take at same time daily
Side Effect
- Hot flushes
- arthralgia
- nausea
- vomiting
- fatigue
- dizziness
- headache
- dyspepsia
- constipation
- diarrhoea
- anorexia
- alopoecia
- increased sweating
- rash
- peripheral oedema
- osteoporosis
- musculoskeletal pain
- vaginal irritation
- Thromboembolic events
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Tamoxifen
|
Plasma levels reduced
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Data not available
|
Data not available
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.