Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Mania
Age: Adult
Condition: Treatment and prevention
Dose: Oral – 400-1,200 mg daily in 1-2 divided doses
Note: Serum lithium should be monitored 12 hours after dose, twice weekly until serum concentration and clinical condition stabilize, and every other month thereafter. Desirable range for serum lithium: 0.6-1.2 mEq/L; although higher serum concentrations may be needed, not to exceed 1.5 mEq/L
Indication: Bipolar disorder
Age: Adult
Condition: Treatment and prevention
Dose: Oral – 400-1,200 mg daily in 1-2 divided doses
Note: Serum lithium should be monitored 12 hours after dose, twice weekly until serum concentration and clinical condition stabilize, and every other month thereafter. Desirable range for serum lithium: 0.6-1.2 mEq/L; although higher serum concentrations may be needed, not to exceed 1.5 mEq/L

Child Dose

Clinical InformationAdministration Information
Indication: Bipolar I Disorder (Acute Manic or Mixed Episodes and Maintenance Treatment)
Age: 7 years and older
Dose: Tablet – 300 mg
Frequency: Three times daily
Note: by mouth (oral)
Indication: Bipolar I Disorder (Acute Manic or Mixed Episodes and Maintenance Treatment)
Age: 7 years and older
Dose: Tablet – 300 mg
Frequency: twice daily
Note: by mouth (oral)

Renal Dose

Clinical InformationAdministration Information
Condition: Renal impairment: Creatinine Clearance 10-50 ml/min
Dose: Dosage Form with Dose – 50-75% of normal dose
Note: Renal impairment dosage recommendation
Condition: Renal impairment: Creatinine Clearance less than 10 ml/min
Dose: Dosage Form with Dose – 25-50% of normal dose
Note: Renal impairment dosage recommendation
Administration
  • Take with food
  • Regular timing
Side Effect

Drug Interaction

Drug NameRisk Factors
Carbonic Anhydrase Inhibitors (Acetazolamide, Dorzolamide, Brinzolamide), Chlorpromazine, Sodium-containing preparations, Theophylline, Urea
Reduced serum levels
Iodine salts
Enhanced hypothyroid effects

Disease Interaction

Disease NameRisk Factors
Renal insufficiency
Risk of lithium toxicity
Cardiovascular insufficiency
Can worsen heart function

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at 25° C

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.