Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Acute exacerbations of chronic bronchitis; Acute otitis media; Urinary tract infections; Gastrointestinal infections; Respiratory and urinary tract infections; Susceptible infections Age: Adult |
Dose: Tablet – 2 tablet of 480 mg Frequency: twice daily Note: In severe cases, 3 times daily. |
|
Indication: Acute exacerbations of chronic bronchitis; Acute otitis media; Urinary tract infections; Gastrointestinal infections; Respiratory and urinary tract infections; Susceptible infections Age: Adult |
Dose: DS Tablet – 1 tablet (960 mg) Frequency: twice daily |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Oral – 8–10 mg TMP/kg/day Frequency: every 12 hours |
|
Indication: UTI prophylaxis Age: Child |
Dose: Oral – 2 mg TMP/kg/day Frequency: every 24 hours |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Adult Condition: Renal impairment |
Dose: Not recommended Note: Dosage Recommendation |
|
Age: Adult Condition: Renal impairment |
Dose: Half the standard dose Note: Dosage Recommendation |
Administration
- Take at regular intervals
- Complete full course
Side Effect
- Allergic myocarditis
- erythema multiforme
- exfoliative dermatitis
- angioedema
- drug fever
- chills
- Henoch-Schoenlein purpura
- serum sickness-like syndrome
- generalised allergic reactions
- generalised skin eruptions
- photosensitivity
- conjunctival and scleral inj
- pruritus
- urticaria
- rash
- periarteritis nodosa
- SLE
- elevated serum transaminase and bilirubin
- pseudomembranous enterocolitis
- pancreatitis
- stomatitis
- glossitis
- nausea
- emesis
- abdominal pain
- diarrhoea
- anorexia
- renal failure
- interstitial nephritis
- elevated BUN and serum creatinineeatinine
- toxic nephrosis w/ oliguria and anuria
- hyperkalaemia
- aseptic meningitis
- convulsions
- peripheral neuritis
- ataxia
- vertigo
- tinnitus
- headache
- hallucinations
- depression
- apathy
- nervousness
- dieresis
- hypoglycaemia
- arthralgia
- myalgia
- rhabdomyolysis
- cough
- shortness of breath
- pulmonary infiltrates
- weakness
- fatigue
- insomnia
- QT prolongation
- haemolysis
- impaired phenylalanine metabolism
- Severe skin
- hepatic and blood disorders
- aplastic anaemia
- hypersensitivity of the resp tract
- Stevens-Johnson syndrome
- toxic epidermal necrolysis
- Clostridium difficile-associated diarrhoea
- severe and symptomatic hyponatraemia
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Ciclosporin
|
Reduced concentrations in blood
|
|
Methotrexate
|
Increases toxicity
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Severe Hepatic Failure/Liver Damage
|
Can cause liver failure
|
|
Serious Haematological Disorders
|
Can worsen blood problems
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.