Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: General Dosing Guidelines Age: Adult |
Dose: by mouth – 250-500 mg Frequency: every 6 hours |
|
Indication: General Dosing Guidelines Age: Adult |
Dose: intravenous/intramuscular – 1-2 g Frequency: every 4-6 hours Note: not to exceed 12 g/day |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Susceptible infections Age: Child |
Dose: Oral – 50–100 mg/kg/day Frequency: divided every 6 hours |
|
Indication: Susceptible infections Age: Child |
Dose: Oral – 1–2 g/day Frequency: divided every 6 hours |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment with Creatinine Clearance less than 10 mL/min |
Dose: Administer Frequency: every 12 to 24 hours |
|
Condition: Renal impairment with Creatinine Clearance 10 to 50 mL/min |
Dose: Administer Frequency: every 6 to 12 hours |
Administration
- Take on empty stomach
- Take 1 hour before meals
Side Effect
- GI upset
- nausea
- vomiting
- diarrhoea
- blood dyscrasias
- urticaria
- exfoliative dermatitis
- rash
- fever
- seizures
- interstitial nephritis
- Anaphylactic shock
- pseudomembranous colitis
- neuromuscular hypersensitivity
- electrolyte imbalance
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Oral contraceptives
|
May reduce efficacy
|
|
Warfarin, Phenindione
|
May alter INR
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Infectious Mononucleosis
|
Risk of skin rash
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store between 20-25° C. Reconstituted oral susp: Store between 2-8° C (discard after 14 days).
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.