Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Depression Age: Adult |
Dose: Oral as hydrochloride – 25-75 mg Frequency: daily in 3 divided doses Note: Gradually increased in 25 mg increments at 1-2 week intervals to 150 mg/day if necessary. |
|
Indication: Depression Age: Adult Condition: Severely depressed |
Dose: Oral as hydrochloride – Up to 225 mg Frequency: daily |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Form – Not specified Note: Safety and efficacy not established |
Administration
- Can take with/without food
- Regular timing
Side Effect
- Fatigue
- Sedation
- Lethargy
- Weakness
- Constipation
- Dry mouth
- Blurred vision
- Agitation
- Anxiety
- Headache
- Insomnia
- Nausea
- Vomiting
- Sweating
- Orthostatic hypotension
- ECG changes
- tachycardia
- Confusion
- EPS
- dizziness
- paresthesia
- tinnitus
- Rash
- Incr LFTs
- Sexual dysfunction
- Seizure
- Agranulocytosis
- Thrombocytopenia
- Eosinophilia
- Leukopenia
- SIADH
- Seizures
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
MAOIs (Phenelzine, Tranylcypromine, Selegiline, Moclobemide)
|
Interaction mentioned but effect not specified
|
|
Alcohol
|
Increase in sedative effect
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Preexisting CV insufficiency
|
Can worsen heart condition
|
|
Epilepsy
|
Risk of seizures
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.