Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Adult |
Dose: by mouth – 25 mg/day Frequency: every 8 hours Note: May adjust gradually. |
|
Age: Adult |
Dose: by mouth – 50-100 mg Frequency: three times daily Note: Maintenance dose. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Not applicable – No approved pediatric dosage available Note: No approved pediatric dosage available |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal Impairment |
Dose: Dosage – less than 25 Note: Contraindicated |
Administration
- Take with the first bite of each main meal
- Must be taken with food
Side Effect
- abdominal pain (19%)
- diarrhea (31%)
- elevated serum transaminases
- flatulence (74%)
- Hepatotoxicity
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Insulin, Other Antidiabetics (Metformin, Glibenclamide, Glimepiride, Sitagliptin, Pioglitazone, Rosiglitazone, Empagliflozin)
|
May enhance effects
|
|
Charcoal, Digestive Enzyme Preparations (Pancreatin, Pancrelipase) containing carbohydrate splitting enzymes
|
Diminished effects
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Diabetic Ketoacidosis, Cirrhosis
|
Can worsen metabolic complications
|
|
Malabsorption, Inflammatory Bowel Disease
|
Can worsen digestive problems
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store below 25° C. Protect from moisture.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.