Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Adjunct in cortical myoclonus Age: Adult |
Dose: Oral – 7.2 g daily Frequency: in 2-3 divided doses Note: increased by 4.8 g/day every 3-4 days. Maximum dose: 20 g daily. |
|
Indication: Cognitive enhancer in cerebrocortical insufficiency Age: Adult |
Dose: Oral – 2.4 g daily Frequency: given as 2-3 divided doses Note: Up to 4.8 g daily may be used in severe cases. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: less than 16 years old |
Dose: not recommended |
|
Age: greater than 16 years old |
Dose: 50 mg/kg of body weight Frequency: three divided doses Note: Once the desired results has been obtained, reduce the initial dose by half. |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment with Creatinine Clearance 50-79 ml/min |
Dose: dosage form not specified – 2/3 usual dose Note: Renal impairment dosage recommendation |
|
Condition: Renal impairment with Creatinine Clearance 30-49 ml/min |
Dose: dosage form not specified – 1/3 usual dose Note: Renal impairment dosage recommendation |
Administration
- May be taken with or without food
- Take with water or soft drink
Side Effect
- Hyperkinesia
- nervousness
- depression
- diarrhoea
- rashes
- CNS stimulation
- sleep disturbances
- dizziness
- excitement
- insomnia
- somnolence
- weight gain
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Warfarin
|
May increase prothrombin time
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Hepatic Impairment
|
Can accumulate in body causing toxicity
|
|
Severe Renal Impairment
|
Drug cannot be properly eliminated
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool and dry place at a temperature below 30˚C , Keep away from sunlight. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.