Medicine Overview

Indication
Know Medicine, Follow Guideline

Adult Dose
Clinical InformationAdministration Information
Indication: Prophylaxis against urothelial toxicity
Condition: With Ifosfamide (if receiving 1.2 grams/square meter ifosfamide dose)
Dose: Intravenous push – 240 mg/square meter
Frequency: 15 minutes before and 4 and 8 hours after ifosfamide administration
Note: Adjust dose accordingly if ifosfamide dose changes. Also given by alternative intravenous push regimens, intermittent infusion or continuous infusion.
Indication: Prophylaxis against urothelial toxicity
Condition: With Ifosfamide (if receiving 1.2 grams/square meter ifosfamide dose)
Dose: Intravenous push – 240 mg/square meter
Frequency: 15 minutes before ifosfamide administration
Note: Followed by oral doses. Adjust dose accordingly if ifosfamide dose changes. Also given by alternative intravenous push regimens, intermittent infusion or continuous infusion.

Child Dose
Clinical InformationAdministration Information
Age: Child
Dose: Tablet – No approved pediatric dosage available
Note: No approved pediatric dosage available
Administration
  • Given through IV or infusion
  • Should be given 15 minutes before chemotherapy
Side Effect

Drug Interaction
Drug NameRisk Factors
Cisplatin, Nitrogen mustard
Incompatible in vitro

Disease Interaction
Disease NameRisk Factors
No specific contraindications listed
Monitor for general reactions

Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Should be stored at 15-30° C.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.