Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Stable angina Age: Adult |
Dose: Sustained-release tablet/capsule – 2.6-6.4 mg Frequency: 3-4 times daily Note: Adjust according to response. Maximum: 26 mg 4 times daily. |
|
Indication: Angina Pectoris (Acute Relief) |
Dose: Sublingual Tablet – 0.5 mg Frequency: sublingually every 5 minutes up to 3 times Note: Use at first sign of angina. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: No approved pediatric dosage available Note: Not recommended |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal Failure |
Dose: Not specified – Not specified Frequency: every 24-72 hours |
|
Condition: Renal Failure |
Dose: Not specified – Not specified Frequency: every 72-96 hours |
Administration
- Use as directed
- Place under tongue
Side Effect
- Headache
- Hypotension
- Tachycardia
- Dizziness
- Lightheadedness
- Blurred vision
- Flushing
- N/V
- Nervousness
- Xerostomia
- Methemoglobinemia (rare)
- Syncope
- Prolonged bleeding time
- Exfoliative dermatitis
- Unstable angina
- Rebound hypertension
- Thrombocytopenia
- Dry mouth
- localised burning sensation
- Buccal tablets Delayed dissolution
- may be swallowed by mistake
- Hypotension
- paradoxical bradycardia
- impaired respiration
- syncope and collapse
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Pancuronium
|
May prolong pancuronium-induced neuromuscular blockade
|
|
Dihydroergotamine
|
Enhances bioavailability
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Severe Hypotension
|
Can dangerously lower blood pressure
|
|
Heart Failure
|
Can worsen cardiac function
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.