Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Uncomplicated lower urinary tract infections Age: Adult |
Dose: Oral – 1 g Frequency: 4 times daily Duration: 1-2 weeks |
|
Indication: Uncomplicated lower urinary tract infections (Long-term therapy) Age: Adult |
Dose: Oral – 2 g Frequency: daily |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Uncomplicated lower urinary tract infections Age: greater than 3 months |
Dose: Oral – 50 mg/kg daily Frequency: in 4 equally divided doses |
|
Indication: Uncomplicated lower urinary tract infections Age: greater than 3 months Condition: Long-term therapy |
Dose: Oral – 30 mg/kg daily Note: Reduce dose to 30 mg/kg daily |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Dose – Reduced doses should be considered Note: Renal impairment: Reduced doses should be considered. |
Administration
- Should be taken with food
- Take with full glass of water
Side Effect
- Nausea
- vomiting
- diarrhoea
- abdominal pain
- photosensitivity reactions
- allergic rash
- urticaria
- pruritus
- visual disturbances
- headache
- dizziness or vertigo
- drowsiness
- confusion
- depression
- excitement
- hallucinations
- toxic psychoses or convulsions (especially after large doses)
- intracranial hypertension (especially in infants and young children)
- metabolic acidosis
- peripheral neuropathies
- muscular weakness
- myalgia
- arthralgia
- tendon damage
- cholestatic jaundice
- thrombocytopenia
- leucopenia
- Erythema multiforme and Stevens-Johnson syndrome
- anaphylactoid reactions
- Auto-immune haemolytic anaemia (particularly in elderly patients)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Sucralfate, Aluminium, Calcium, Iron, Magnesium, Zinc
|
Absorption reduced
|
|
Probenecid
|
Excretion reduced and plasma concentrations increased
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
History of Convulsive Disorders
|
Risk of seizures
|
|
Porphyria
|
Can trigger acute attacks
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.