Medicine Overview

Indication

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Adult Dose

Clinical InformationAdministration Information
Indication: Chemotherapy Induced Nausea and Vomiting
Age: Adult
Dose: Oral – 1 mg
Frequency: by mouth 1 hour before chemotherapy, then 1 mg 12 hours after 1st dose; OR 2 mg 1 hour before chemotherapy
Indication: Chemotherapy Induced Nausea and Vomiting
Age: Adult
Dose: Intravenous – 0.01 mg/kg/dose
Note: infused over 5 minutes or direct injected over 30 seconds, 30 minutes before chemotherapy

Child Dose

Clinical InformationAdministration Information
Indication: Chemotherapy Induced Nausea and Vomiting
Age: less than 2 years
Dose: intravenous – Dosage not established
Note: Safety and efficacy not established
Indication: Chemotherapy Induced Nausea and Vomiting
Age: 2-16 years
Dose: intravenous – 0.01 mg/kg
Note: infused over 5 minutes or direct injection over 30 seconds, 30 minutes before chemotherapy

Renal Dose

Clinical InformationAdministration Information
Condition: Severe (creatinine clearance less than 30 mL/minute)
Dose: Intravenous – 40 mcg/kg
Note: Total clearance was not affected in patients with severe renal failure who received a single dose
Condition: Renal impairment
Dose: By mouth – No dosage adjustment required
Note: No dosage adjustment required
Administration
  • Take up to 1hr before chemotherapy
  • Can take with/without food
Side Effect

Drug Interaction

Drug NameRisk Factors
Phenobarbital
May induce metabolism of granisetron

Disease Interaction

Disease NameRisk Factors
No specific contraindications listed
Monitor for general drug reactions

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store between 15-30°C. Protect from light.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.