Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Prophylaxis of neurological deficit following subarachnoid haemorrhage Age: Adult |
Dose: Oral – 60 mg Frequency: every 4 hours Duration: 21 consecutive days Note: Beginning within 4 days of onset of haemorrhage. |
|
Indication: Prophylaxis of neurological deficit following subarachnoid haemorrhage Condition: Hepatic impairment |
Dose: Oral – 30 mg Frequency: every 4 hours Note: Initial dose. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Form – No approved pediatric dosage available Note: No approved pediatric dosage available |
Administration
- Capsule: Take on empty stomach
- Tablet: May take with/without food
Side Effect
- Reduction in systemic blood pressure (1-8%)
- Diarrhea (2-4%)
- Headache (1-4%)
- Abdominal discomfort (2%)
- Rash (1-2%)
- Heart failure
- Arrhythmia
- Anemia
- ECG abnormalities
- GI hemorrhage
- Hepatitis
- Jaundice
- Thrombocytopenia
- Vomiting
- Thrombosis
- Rebound vasospasm
- Angina/MI
- symptomatic hypotension
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Rifampicin, Carbamazepine, Phenobarbital, Phenytoin
|
Plasma concentration and efficacy may be significantly reduced
|
|
Phenytoin
|
May increase serum levels and toxicity
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Recent MI or Unstable Angina
|
Risk of cardiovascular complications
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store between 15-30° C. Protect from light.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.