Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Short-term management of insomnia Age: Adult |
Dose: Oral – 7.5-15 mg Frequency: at bedtime Note: Hepatic impairment: Mild to moderate: Dosage reduction needed. Severe: Contraindicated. |
|
Indication: Short-term management of insomnia Age: Elderly |
Dose: Oral – 7.5 mg Frequency: at bedtime Note: Hepatic impairment: Mild to moderate: Dosage reduction needed. Severe: Contraindicated. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Seizures Age: 3-6 months Condition: Hospital setting |
Dose: Oral – 2.5 mg Note: Doses are given as single dose |
|
Indication: Seizures Age: greater than 6 months to less than 1 year Condition: Hospital setting |
Dose: Oral – 2.5 mg Note: Doses are given as single dose |
Administration
- May be taken with or without food
- IV should be given very slowly
Side Effect
- Decreased respiratory rate (23%)
- Apnea (15%)
- Drowsiness (1-5%)
- Seizure-like activity (1%)
- Nausea/vomiting (3%)
- Cough (1%)
- Pain at injection site (4-5%)
- Headache
- Sedation
- HicCough
- Delirium
- Euphoria
- Desaturation
- Hypotension
- Seizurelike activity
- Nystagmus
- Paradoxical reactions
- HicCough
- Apnea
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Alcohol, Opioids, Barbiturates, Sedatives, Anaesthetics
|
Increased CNS depression
|
|
Opiates, Phenobarbital, Other Benzodiazepines (Diazepam, Alprazolam, Lorazepam, Clonazepam, Midazolam)
|
Increased respiratory depression
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Severe Respiratory Failure
|
Can worsen breathing function
|
|
Acute Respiratory Depression
|
Can further suppress breathing
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Protect from light and moisture, store in cool and dry place. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.