Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Erosive Esophagitis Associated With GERD Treatment |
Dose: Oral – 40 mg Frequency: once daily Duration: 8-16 weeks |
|
Indication: Erosive Esophagitis Associated With GERD Maintenance of healing |
Dose: Oral – 40 mg Frequency: once daily |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Erosive Esophagitis Associated With GERD Age: less than 5 years |
Dose: PO – 20 mg or 40 mg Note: Safety and efficacy not established |
|
Indication: Erosive Esophagitis Associated With GERD Age: greater than 5 years |
Dose: PO – 20 mg Frequency: once daily Duration: up to 8 weeks Note: by mouth (oral) |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Form – Not specified Note: Renal impairment: No dosage adjustment needed. |
Administration
- Take on empty stomach
- Take 1 hour before meals
Side Effect
- Headache (More than 4%)
- Abdominal pain (4%)
- Facial edema (Less than 4%)
- Generalized edema (Less than 2%)
- Chest pain (4%)
- Diarrhea (4%)
- Constipation (Less than 4%)
- Pruritus (4%)
- Rash (4%)
- Flatulence (Less than 4%)
- Hyperglycemia (1%)
- Nausea (1%)
- Vomiting (More than 4%)
- Photosensitivity (Less than 2%)
- Angioedema
- Atrophic gastritis
- Anterior ischemic optic neuropathy
- Hepatocellular damage leading to hepatic failure
- Interstitial nephritis
- Pancreatitis
- Pancytopenia
- Rhabdomyolysis
- Risk of anaphylaxis
- Stevens-Johnson syndrome
- Fatal toxic epidermal necrolysis
- Erythema multiforme
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Digoxin
|
Increased risk of cardiotoxic effects
|
|
Diuretics (Chlorothiazide, Chlorthalidone, Hydrochlorothiazide, Indapamide, Metolazone, Bumetanide, Ethacrynic acid, Furosemide, Torsemide, Amiloride, Eplerenone, Spironolactone, Triamterene)
|
Increased risk of hypomagnesaemia
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for general reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep in a dry place, away from light and heat. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.