Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Bacterial endocarditis
Age: Adult
Condition: With aminoglycoside
Dose: Intravenous – 1.2 g
Frequency: every 4 hours
Indication: Intrapartum prophylaxis against group B streptococcal infection
Age: Adult
Dose: Intravenous – Initial: 3 g, then 1.5 g
Frequency: every 4 hours
Duration: until delivery
Note: Initial dose is 3 g, then 1.5 g every 4 hours until delivery.

Child Dose

Clinical InformationAdministration Information
Indication: Bacterial Infection
Age: Infant & Children
Dose: Intravenous – 100,000–250,000 U/kg/day
Frequency: every 4–6 hours
Note: Maximum daily dose is 24 million U.
Indication: Bacterial Infection
Age: Infant & Children
Dose: Intramuscular – 100,000–250,000 U/kg/day
Frequency: every 4–6 hours
Note: Maximum daily dose is 24 million U.

Renal Dose

Clinical InformationAdministration Information
Condition: Renal impairment
Dose: Not specified – Not specified
Note: Dosing interval should be no more frequent than every 8-10 hours
Administration
  • Hospital use only
  • Given by injection
Side Effect

Drug Interaction

Drug NameRisk Factors
Probenecid
Increases and prolongs serum penicillin levels
Tetracycline
May antagonize the bactericidal effect of penicillin

Disease Interaction

Disease NameRisk Factors
No specific contraindications listed
Monitor for general drug reactions

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store between 20-25°C. Reconstituted soln: Store between 2-8°C.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.