Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Type 2 diabetes mellitus Age: Adult |
Dose: Oral – 0.5 mg Frequency: before main meals Note: Usual initial dose. Max dose: 16 mg daily. Hepatic impairment: May require longer intervals between dosage adjustments. |
|
Indication: Type 2 diabetes mellitus Age: Adult Condition: patients who have had previous hypoglycaemic treatment |
Dose: Oral – 1 mg or 2 mg Note: Initial dose. Max dose: 16 mg daily. Hepatic impairment: May require longer intervals between dosage adjustments. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Safety and efficacy not established Note: Not recommended |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal Impairment with Creatinine Clearance 40-80 mL/minute |
Dose: Dosage Form – No adjustments necessary Note: Renal Impairment |
|
Condition: Renal Impairment with Creatinine Clearance 20-40 mL/minute |
Dose: Dosage Form – 0.5 mg Frequency: with meals Note: Titrate slowly and monitor |
Administration
- Take 15 minutes before meals
- No more than 4 meals per day
Side Effect
- Hypoglycaemia
- nausea
- diarrhoea
- constipation
- vomiting
- dyspepsia
- arthralgia
- sinusitis
- rhinitis
- back pain
- rash
- pruritus
- urticaria
- visual disturbances
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Rifampicin, Barbiturates, Carbamazepine
|
May increase repaglinide metabolism
|
|
NSAIDs (Ibuprofen, Naproxen, Diclofenac, Celecoxib, Meloxicam, Indomethacin, Piroxicam, Ketorolac), Salicylates, Sulphonamides, Phenylbutazone, Oral Anticoagulants (Warfarin, Heparin, Dabigatran, Rivaroxaban, Apixaban, Edoxaban), Hydantoins
|
May potentiate action of repaglinide
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Diabetic Ketoacidosis
|
Can worsen condition
|
|
Severe Hepatic Impairment
|
Cannot be properly metabolized
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Do not store above 30°C. Keep away from light and out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.