Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Palliative treatment of prostatic carcinoma Age: Adult |
Dose: Oral – 250 mg Frequency: three times daily Note: Preferably at least 3 days before gonadorelin analogue treatment. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: Tablet – No approved pediatric dosage available Note: No approved pediatric dosage available |
Administration
- Take with or without food
- Take at regular intervals
Side Effect
- Hot flashes (61%)
- Decreased libido (36%)
- Impotence (31%)
- Diarrhea (12%)
- Nausea/vomiting (11%)
- Gynecomastia (9%)
- Anorexia (4%)
- Edema (4%)
- Leukopenia (3%)
- Rash (3%)
- Hemolytic anemia
- methemoglobinemia
- Increased AST
- ALT
- bilirubin
- BUN
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Warfarin
|
Increased prothrombin time in patients on long-term treatment
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Severe Hepatic Impairment
|
Can worsen liver function
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at 25° C.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.