Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Bacterial vaginosis Age: Adult |
Dose: Oral – 2 g Frequency: once daily Duration: 1 day Note: single dose |
|
Indication: Bacterial vaginosis Age: Adult |
Dose: Oral – 2 g Frequency: once daily Duration: 2 consecutive days |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Intestinal amoebiasis Age: Child: greater than 3 years |
Dose: Oral – 50-60 mg/kg Frequency: daily Duration: for 3 consecutive days Note: Maximum: 2 g/day |
|
Indication: Hepatic amoebiasis Age: Child: greater than 3 years |
Dose: Oral – 50-60 mg/kg Frequency: daily Duration: for 5 days Note: Maximum: 2 g/day |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Adult Condition: Renal impairment: Haemodialysis |
Dose: Tablet – half the usual dose Frequency: once Note: Additional dose at the end of haemodialysis |
Administration
- Take with food
- Take during or immediately after meals
Side Effect
- Anorexia (2-3%)
- Constipation (Less than 1%)
- Dizziness (Less than 1%)
- Dysgeusia (4-6%)
- Dyspepsia (1-2%)
- Headache (Less than 1%)
- Nausea (3-5%)
- Vomiting (1-2%)
- Ataxia
- Candida overgrowth
- Convulsions & transient peripheral neuropathy
- Numbness & paresthesia
- Diarrhea
- Darkened urine
- Tongue discoloration
- Hypersensitivity
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Oral Anticoagulants (Warfarin, Heparin, Dabigatran, Rivaroxaban, Apixaban, Edoxaban)
|
May potentiate the effects resulting in prolonged prothrombin time
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Blood Dyscrasias
|
Can worsen blood disorders
|
|
Neurologic Disorders
|
Can cause neurological problems
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at room temperature & protected from light.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.