Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Chronic hepatitis B Age: Adult |
Dose: Oral – 300 mg Frequency: once daily |
|
Indication: HIV infection Age: Adult Condition: In combination with other antiretroviral agents |
Dose: Oral – 300 mg Frequency: once daily |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: HIV Infection Age: less than 2 years |
Dose: Tablet – 300 mg Note: Safety and efficacy not established |
|
Indication: HIV Infection Age: greater than 2 years |
Dose: Tablet – 8 mg/kg Frequency: once daily Note: by mouth (oral); not to exceed 300 mg/day |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment: Haemodialysis patients |
Dose: 300 mg Frequency: once every 7 days or after a cumulative total of 12 hours of dialysis |
|
Condition: Renal impairment: Creatinine Clearance 10-29 ml/min |
Dose: 300 mg Frequency: every 72-96 hours |
Administration
- Can be taken with or without food
- Take at same time daily
Side Effect
- Asthenia (11%)
- Diarrhea (16%)
- Nausea (11%)
- Pain (12%)
- Anorexia
- Depression
- Myalgia
- Peripheral neuropathy
- Dyspepsia
- Rash
- Headache
- Vomiting
- Flatulence
- Abdominal pain
- Neutropenia
- Increased transaminases
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Atazanavir
|
Decreased atazanavir concentration unless co-administered with ritonavir
|
|
Drugs eliminated by active tubular secretion
|
Increased serum concentration of tenofovir or co-administered drug
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Hypersensitivity to Components
|
Can cause severe allergic reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool and dry place, protected from light and moisture. Keep the medicine out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.