Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Contraception |
Dose: Tablet – 1 active tablet (3 mg drospirenone/0.03 mg ethinyl estradiol) Frequency: once daily Duration: for 21 days Note: followed by 1 inert tablet by mouth once daily for 7 days |
|
Indication: Contraception |
Dose: Tablet – 1 active tablet (3 mg drospirenone/0.02 mg ethinyl estradiol) Frequency: once daily Duration: for 24 days Note: followed by 1 inert tablet by mouth once daily for 4 days |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Contraception Age: less than 14 years |
Dose: Not established Note: Safety and efficacy not established |
|
Indication: Contraception Age: greater than 14 years |
Dose: Same dosing as adult Note: Same dosing as adult |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment: Creatinine Clearance (ml/min) less than 50 |
Dose: Not specified – Not specified Note: Avoid use. |
Administration
- Take with or without food
- Take at same time each day
Side Effect
- Premenstrual syndrome (13.2%)
- Migraine/headache (10.7%)
- Breast pain/discomfort/tenderness (8.3%)
- Menstrual irregularities (4.7%)
- Nausea/vomiting (4.5%)
- Abdominal pain/discomfort/tenderness (2.3%)
- Mood changes
- including affect lability
- depression
- alteration of mood
- mood swings
- and irritability (2.3%)
- Irregular uterine bleeding
- Venous/arterial thromboembolic events
- including DVT
- PE
- stroke
- MI
- intracardiac thrombosis
- sagittal sinus thrombosis
- intracranial venous sinus thrombosis
- retinal vein thrombosis
- Hypertension
- Hypersensitivity
- Hyperkalemia
- Chloasma
- Gallbladder disease
- Toxic skin eruption
- Uterine leiomyoma
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
ACE Inhibitors (Captopril, Enalapril, Lisinopril, Ramipril, Benazepril, Fosinopril, Quinapril, Perindopril), Angiotensin II receptor antagonists, Aldosterone antagonists, Potassium salts, NSAIDs (Ibuprofen, Naproxen, Diclofenac, Celecoxib, Meloxicam, Indomethacin, Piroxicam, Ketorolac)
|
Increased risk of hyperkalaemia
|
|
Aminoglutethimide
|
May increase hepatic metabolism of progestins
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Undiagnosed Abnormal Genital Bleeding
|
Risk of masking serious underlying condition
|
|
Renal Insufficiency
|
Can lead to dangerous potassium retention
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store below 30°C. Store all drugs properly and keep them out of reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.